Laura Silvestri

Nationwide Children's Hospital — United States

Medicine · Health Sciences

39h-index7.7kcitations131works1.72yr avg
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Research Topics

Iron Metabolism and Disorders(89), Hemoglobinopathies and Related Disorders(76), Trace Elements in Health(31), Erythropoietin and Anemia Treatment(20), Erythrocyte Function and Pathophysiology(19)

Publications131 total

Tfr2-mediated erythropoiesis expansion controls systemic glucose homeostasis by modulating erythroid metabolic demand
Blood·2025Open Access
When TNFα is out, IFN-γ drives anemia of inflammation
Blood·2025Open Access
Response to Letter to the Editor: “Advancing TMPRSS6‐Targeted Therapy for MASLD: Mechanistic and Translational Perspectives”
Liver International·2025
Targeting the Liver Serine Protease <scp>TMPRSS6</scp> Ameliorates Steatosis and Attenuates Fibrosis in Experimental <scp>MASLD</scp>
Liver International·2025· 4 citedOpen Access
Welcome to Blood Red Cells &amp; Iron
Blood Red Cells & Iron·2025Open Access
Current Landscape of Hepcidin Therapeutics
Advances in experimental medicine and biology·2025· 3 cited
Bone phenotyping of murine hemochromatosis models with deficiencies of Hjv, Alk2, or Alk3: The influence of sex and the bone compartment
The FASEB Journal·2024· 3 citedOpen Access
Hyperactive Erythropoiesis Induced By Hematopoietic <i>Tfr2</i> Deletion Corrects Glucose Abnormalities in β-Thalassemic Mice
Blood·2024Open Access
THU-218 A novel role for the epigenetic regulator SUV420H1 in MASLD and its complications
Journal of Hepatology·2024
Bone marrow <i>Tfr2</i> deletion improves the therapeutic efficacy of the activin‐receptor ligand trap RAP‐536 in β‐thalassemic mice
American Journal of Hematology·2024· 4 citedOpen Access
Ironing erythroid cells takes FLG1 and ERFE to tango
Blood·2024· 2 citedOpen Access
A functional interplay between the two BMP-SMAD pathway inhibitors TMPRSS6 and FKBP12 regulates <i>hepcidin</i> expression in vivo
American Journal of Physiology-Gastrointestinal and Liver Physiology·2024· 4 cited
Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia
Nature Reviews Endocrinology·2023· 2 citedOpen Access
FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
Cell Reports Medicine·2023· 9 citedOpen Access
Flavor of Iron at EHA2023: Novel Regulatory Mechanisms and Therapeutic Options for the Correction of Anemia
HemaSphere·2023Open Access
S282: ERYTHROPOIESIS INDUCTION THROUGH BONE MARROW TFR2 DELETION REDUCES BLOOD GLUCOSE LEVELS IN WILD-TYPE AND Β-THALASSEMIC MICE
HemaSphere·2023Open Access
S285: DISSECTING THE ROLE OF THE IMMUNOPHILIN FKBP12 IN HEPCIDIN REGULATION
HemaSphere·2023· 1 citedOpen Access
P1491: THE DYNAMIC INTERACTION BETWEEN INFLAMMATION AND THE IRON SENSOR HFE, IN SEVERE MALARIA-INDUCED ANEMIA
HemaSphere·2023Open Access
Table of Contents
Kidney International·2023Open Access
BMP-SMAD pathway upregulation in hepatocytes delays NAFLD-NASH development
Journal of Hepatology·2023
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Frequent Co-authors

Clara Camaschella(30), Antonella Nai(23), Alessia Pagani(22), Giorgio Casari(5), Giuliana Ferrari(5), Marco Rausa(5), Alessandro Campanella(4), Luigia De Falco(4), Achille Iolascon(4), Patrizia Rovere‐Querini(4), Maria Rosa Lidonnici(4), Domenico Girelli(4), Mariateresa Pettinato(4), Luigia Atorino(3), Angelo A. Manfredi(3), Caroline Kannengiesser(3), Martina U. Muckenthaler(3), Giacomo Mandelli(3), Natascia Campostrini(3), Irene Artuso(3)