Akeo Shinkai

Tokyo Institute of Technology — Japan

Materials Science · Physical Sciences

26h-index3.1kcitations132works9.02yr avg
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Research Topics

Enzyme Structure and Function(57), Bacterial Genetics and Biotechnology(29), Protein Structure and Dynamics(20), RNA and protein synthesis mechanisms(18), CRISPR and Genetic Engineering(15)

Publications132 total

Nkx2.5 triggers vascular remodeling in chicken but not in emu wing mesoderm
Developmental Biology·2025Open Access
The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS
Nucleic Acids Research·2024· 18 citedOpen Access
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation
Nature Communications·2021· 86 citedOpen Access
SCOPE: Flexible targeting and stringent CARF activation enables type III CRISPR-Cas diagnostics
2021· 8 citedOpen Access
Reconstitution of Thermus thermophilus CRISPR-Cmr complex using E. coli cell-free protein synthesis method
The Molecular Biology Society of Japan·2016
[Structure and function of Type III-B CRISPR-Cmr complex from Thermus thermophilus].
PubMed·2015
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
Science·2015· 139 citedOpen Access
高度好熱菌Thermus thermophilus由来Type III-B CRISPR-Cmr複合体の構造と機能
2015
Structural and functional characterization of transcriptional repressor CsoR from Thermus thermophilus HB8
Microbiology·2014
RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus
Molecular Cell·2014· 307 citedOpen Access
LdrP, a cAMP receptor protein/FNR family transcriptional regulator, serves as a positive regulator for the light-inducible gene cluster in the megaplasmid of Thermus thermophilus
Microbiology·2014· 21 cited
Genome-wide comprehensive analysis of transcriptional regulation by ArgR in Thermus thermophilus
Extremophiles·2014· 8 cited
Correction for Shinkai et al., Identification of Promoters Recognized by RNA Polymerase-σ <sup>E</sup> Holoenzyme from Thermus thermophilus HB8
Journal of Bacteriology·2014Open Access
Global gene expression mediated by <i>Thermus thermophilus</i> <scp>SdrP</scp>, a <scp>CRP/FNR</scp> family transcriptional regulator
Molecular Microbiology·2014Open Access
The role of ribonucleases in regulating global mRNA levels in the model organism Thermus thermophilus HB8
BMC Genomics·2014· 22 citedOpen Access
Structure and Function of CRISPR-Cas System
Seibutsu Butsuri·2014Open Access
Structure and Activity of the RNA-Targeting Type III-B CRISPR-Cas Complex of Thermus thermophilus
Molecular Cell·2013· 234 citedOpen Access
Crystal structure of the C-terminal domain of Themus thermophilus LitR in complex with cobalamin
2013
Integrated database of information from structural genomics experiments
Acta Crystallographica Section D Biological Crystallography·2013· 2 cited
Structure and function of a TetR family transcriptional regulator, SbtR, from <i>thermus thermophilus</i> HB8
Proteins Structure Function and Bioinformatics·2013· 11 cited
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Frequent Co-authors

Seiki Kuramitsu(22), Shigeyuki Yokoyama(19), Yoshihiro Agari(18), Keiko Sakamoto(10), Noriko Nakagawa(6), Thirumananseri Kumarevel(6), Yoshitaka Bessho(5), Raymond H.J. Staals(4), Yifan Zhu(4), David W. Taylor(4), John van der Oost(4), Tomoyuki Tanaka(4), Akio Ebihara(4), Jennifer A. Doudna(3), Hideharu Anazawa(3), Lawrence A. Loeb(3), Shôji Mizushima(3), Kazuko Agari(3), Subash C. B. Gopinath(3), Penmetcha K. R. Kumar(3)