Justin C. Deme

National Institutes of Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.3kcitations127works3.12yr avg
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Research Topics

Bacterial Genetics and Biotechnology(35), Bacteriophages and microbial interactions(26), RNA and protein synthesis mechanisms(17), Photosynthetic Processes and Mechanisms(12), Advanced Electron Microscopy Techniques and Applications(11)

Publications127 total

Mechanistic insights into RNA chaperoning by Ro60 and La autoantigens
Cell·2026Open Access
D43m3 apo-form
Biological Magnetic Resonance Bank·2026Open Access
D43m3 apo-form
Open MIND·2026
Structure of the conjugation surface exclusion protein TraT
Communications Biology·2025Open Access
Identification and Characterization of a Small Molecule Ligand for the Huntingtin-HAP40 Complex
2025Open Access
A shared mechanism for Bacteroidota protein transport and gliding motility
Nature Communications·2025Open Access
Distinct immunity protein families mediate compartment-specific neutralization of a bacterial toxin
Cell Reports·2025· 1 citedOpen Access
Mechanism of phosphoinositide regulation of lysosomal pH via inhibition of CLC-7
2025Open Access
A new paradigm for outer membrane protein biogenesis in the Bacteroidota
Nature·2025· 1 citedOpen Access
Structure and substrate recognition by the Twin-arginine translocation (Tat) pathway core complex
2025Open Access
The discovery of a <i>Legionella</i> phage explains a key determinant of human disease
Science Advances·2025Open Access
SLC45A4 is a pain gene encoding a neuronal polyamine transporter
Nature·2025· 5 citedOpen Access
High-Affinity, Structure-Validated and Selective Macrocyclic Peptide Tools for Chemical Biology Studies of Huntingtin
2025· 1 citedOpen Access
Structural basis for transport and inhibition of nucleotide sugar transport in pathogenic fungi
2025Open Access
Cryo-EM structure of Candida albicans Vrg4 bound to an inhibitory nanobody.
2025
Cryo-EM structure of Candida albicans Vrg4 bound to an inhibitory nanobody and GDP-Mannose.
2025
Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay
Nature Communications·2025· 2 citedOpen Access
Probabilistic single-particle cryo-EM <i>ab initio</i> 3D reconstruction in <i>SIMPLE</i>
Acta Crystallographica Section D Structural Biology·2025Open Access
Distinct immunity protein families mediate compartment-specific neutralisation of a bacterial toxin
2025· 1 citedOpen Access
Structure of the conjugation surface exclusion protein TraT
2025· 1 citedOpen Access
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Frequent Co-authors

Susan M. Lea(46), Steven Johnson(25), Lucas Kuhlen(11), Joseph J. E. Caesar(11), Ben C. Berks(10), James W. Coulton(7), Emily Furlong(7), Joanne L. Parker(6), Simon Newstead(6), Rory Hennell James(6), Felicity Alcock(6), Gabriel Kuteyi(5), Frédéric Lauber(5), Patrizia Abrusci(5), Samuel Wagner(5), Tracy Palmer(5), Philip C. Biggin(4), Phillip J. Stansfeld(4), Fabienne F. V. Chevance(4), Kelly T. Hughes(4)