Pavel A. Petukhov

University of Illinois Chicago — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index2.7kcitations118works2.72yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(20), Protein Degradation and Inhibitors(16), Computational Drug Discovery Methods(14), Chemical Synthesis and Analysis(12), Redox biology and oxidative stress(8)

Publications118 total

Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy
Redox Biology·2025Open Access
Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy
2025Open Access
Targeting Apicomplexan Parasites: Structural and Functional Characterization of <i>Cryptosporidium</i> Thioredoxin Reductase as a Novel Drug Target
Biochemistry·2025· 1 cited
Abstract 5982: Mechanisms underlying the anti-cancer activity of new, non-covalent thioredoxin reductase inhibitors
Cancer Research·2025
Abstract 3042: Non-covalent thioredoxin reductase inhibitors for TNBC
Cancer Research·2025
Pleiotropic anti-cancer activities of novel non-covalent thioredoxin reductase inhibitors against triple negative breast cancer
Free Radical Biology and Medicine·2024· 7 citedOpen Access
Effects of Angiotensin-I-Converting Enzyme (ACE) Mutations Associated with Alzheimer’s Disease on Blood ACE Phenotype
Biomedicines·2024· 1 citedOpen Access
The “Doorstop Pocket” In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery
Journal of Medicinal Chemistry·2024· 10 citedOpen Access
Crystal structures of human histone deacetylase 8 in complex with novel hydroxamic acid inhibitors
Acta Crystallographica Section A Foundations and Advances·2024Open Access
Effects of ACE Mutations Associated with Alzheimer’s Disease on Blood ACE Phenotype
Preprints.org·2024· 2 citedOpen Access
ACE Phenotyping in Human Blood and Tissues: Revelation of ACE Outliers and Sex Differences in ACE Sialylation
Biomedicines·2024· 5 citedOpen Access
Carriers of Heterozygous Loss-of-Function ACE Mutations Are at Risk for Alzheimer’s Disease
Biomedicines·2024· 12 citedOpen Access
Method for Measuring the Mass Fraction of Soybean Trypsin Inhibitor: Features of Development and Certification
Measurement Standards Reference Materials·2024Open Access
On Developing Metrological Assurance to Identify and Quantify the Content of Non-infectious Food Protein Allergens of Animal or Plant Origin in Food Products
2024
On the Development of Metrological Support for the Identification and Quantitative Determination of the Content of Non-infectious Food Allergens of Animal or Plant Protein Origin in Food Products
Measurement Standards Reference Materials·2023· 2 citedOpen Access
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo
Nature Communications·2023· 29 citedOpen Access
Targeting EB3–IP3R3 Interface with Cognate Peptide Protects from Acute Respiratory Distress Syndrome
American Journal of Respiratory Cell and Molecular Biology·2023· 7 citedOpen Access
Urinary ACE Phenotyping as a Research and Diagnostic Tool: Identification of Sex-Dependent ACE Immunoreactivity
Biomedicines·2023· 10 citedOpen Access
Carriers of heterozygous loss-of-function ACE mutations are at risk for Alzheimer’s disease
Research Square (Research Square)·2023· 1 citedOpen Access
Blood ACE Phenotyping for Personalized Medicine: Revelation of Patients with Conformationally Altered ACE
Biomedicines·2023· 8 citedOpen Access
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Frequent Co-authors

Alan P. Kozikowski(19), Gregory R. J. Thatcher(10), Qiang Yu(7), Michael Brunsteiner(5), Sylvie Y. Blond(5), Aleksey V. Rukavishnikov(4), John F. W. Keana(4), Francesco Angelucci(4), David L. Williams(4), Subash Velaparthi(3), Raghupathi Neelarapu(3), He Bai(3), Quan Li(3), Tatiana O. Zaikova(3), Emma Mendonca(3), Valentina Petukhova(3), Haining Lyu(3), Hazem Abdelkarim(3), Zhi-Liang Wei(3), Yingxian Xiao(3)