Katherine S. Barker

St. Jude Children's Research Hospital — United States

Medicine · Health Sciences

40h-index5.5kcitations82works2.02yr avg
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Research Topics

Antifungal resistance and susceptibility(54), Fungal Infections and Studies(38), Pneumocystis jirovecii pneumonia detection and treatment(17), Fungal and yeast genetics research(8), Fungal Biology and Applications(6)

Publications82 total

Relative contributions of the ERG11VF125AL and MRR1AN647T mutations to fluconazole resistance in Clade III Candidozyma (Candida) auris clinical isolates
Clinical Microbiology and Infection·2025Open Access
Mutations in <i>TAC1B</i> drive increased <i>CDR1</i> and <i>MDR1</i> expression and azole resistance in <i>Candida auris</i>
Antimicrobial Agents and Chemotherapy·2025Open Access
Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in <i>Candida auris</i> ( <i>Candidozyma auris</i> ), <i>Candida albicans</i> , <i>Candida parapsilosis</i> , and <i>Candida glabrata</i> ( <i>Nakaseomyces glabratus</i> )
Antimicrobial Agents and Chemotherapy·2025· 2 citedOpen Access
Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in <i>Candida auris</i> , <i>Candida albicans</i> , <i>Candida parapsilosis</i> , and <i>Candida glabrata</i> ( <i>Nakaseomyces glabratus</i> )
2025Open Access
Relative contributions of the <i>ERG11</i> <sup>VF125AL</sup> and <i>MRR1A</i> <sup>N647T</sup> mutations to fluconazole resistance in Clade III <i>Candidozyma</i> ( <i>Candida</i> ) <i>auris</i> clinical isolates
2025· 2 cited
Mutations in <i>TAC1B</i> drive <i>CDR1</i> and <i>MDR1</i> expression and azole resistance in <i>C. auris</i>
2025· 6 citedOpen Access
Probing gene function in <i>Candida albicans</i> wild-type strains by Cas9-facilitated one-step integration of two dominant selection markers: a systematic analysis of recombination events at the target locus
mSphere·2024· 2 citedOpen Access
The zinc cluster transcription factor Znc1 regulates Rta3-dependent miltefosine resistance in <i>Candida albicans</i>
mSphere·2024· 3 citedOpen Access
Mutations in TAC1 and ERG11 are major drivers of triazole antifungal resistance in clinical isolates of Candida parapsilosis
Clinical Microbiology and Infection·2023· 21 citedOpen Access
A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis via altered secretion of candidalysin
Access Microbiology·2021Open Access
In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris
Clinical Microbiology and Infection·2021· 115 citedOpen Access
Delineation of the Direct Contribution of Candida auris <i>ERG11</i> Mutations to Clinical Triazole Resistance
Microbiology Spectrum·2021· 62 citedOpen Access
<i>In vivo</i> emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in <i>Candida auris</i>
2021· 2 citedOpen Access
A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis
PLoS Pathogens·2021· 69 citedOpen Access
Chapter 5: Immunology
The American Pharmacists Association eBooks·2020
Mutations in <i>TAC1B</i> : a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris
mBio·2020· 188 citedOpen Access
IL17 and <i>Candida albicans</i> colonization in the vaginal mucosa
The Journal of Immunology·2020
Characterization of the Efflux Capability and Substrate Specificity of Aspergillus fumigatus PDR5-like ABC Transporters Expressed in Saccharomyces cerevisiae
mBio·2020· 33 citedOpen Access
Mutations in <i>TAC1B</i> : a novel genetic determinant of clinical fluconazole resistance in <i>C. auris</i>
2020· 4 citedOpen Access
The Interleukin (IL) 17R/IL-22R Signaling Axis Is Dispensable for Vulvovaginal Candidiasis Regardless of Estrogen Status
The Journal of Infectious Diseases·2019· 41 citedOpen Access
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Frequent Co-authors

P. David Rogers(36), Jeffrey M. Rybak(8), Teresa T. Liu(8), Glen E. Palmer(8), Elizabeth L. Berkow(7), Joachim Morschhäuser(7), Ramin Homayouni(7), Josie E. Parker(5), Hubertine M. E. Willems(5), Brian M. Peters(5), Sarah Whaley(4), Andrew T. Nishimoto(4), Martine Raymond(4), Laura A. Doorley(3), Sadri Znaidi(3), Lijing Xu(3), Kelly E. Caudle(3), Nathan P. Wiederhold(3), Nigel Cook(3), C.A. Paton(3)