Hiroshi Onuma

Ehime University — Japan

Medicine · Health Sciences

36h-index3.6kcitations125works3.02yr avg
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Research Topics

Adipokines, Inflammation, and Metabolic Diseases(28), Regulation of Appetite and Obesity(18), Adipose Tissue and Metabolism(18), Pancreatic function and diabetes(14), Diabetes Management and Research(11)

Publications125 total

Fulminant Type 1 Diabetes Caused by DIHS Could Be Affected by the Reactivation of HHV-6
The Journal of Clinical Endocrinology & Metabolism·2024· 3 citedOpen Access
Association between serum concentrations of perfluoroalkyl substances and global DNA methylation levels in peripheral blood leukocytes of Japanese women: A cross-sectional study
The Science of The Total Environment·2022· 13 cited
Recurrent Hypoglycemia Due to a High Titer of Insulin Antibody in Response to Exogenous Insulin Administration in Two Cases of Type 1 Diabetes
Internal Medicine·2021· 3 citedOpen Access
Serum perfluoroalkyl substances and breast cancer risk in Japanese women: A case-control study
The Science of The Total Environment·2021· 48 cited
Abstract PD1-09: Safety and efficacy results from the phase 1/2 study of U3-1402, a human epidermal growth factor receptor 3 (HER3)-directed antibody drug conjugate (ADC), in patients with HER3-expressing metastatic breast cancer (MBC)
Cancer Research·2021· 8 cited
Incentive for Adopting the Consolidated Tax Return System, and Its Relation to Corporate Governance, and Tax Avoidance: Evidence from Japan.
2020Open Access
Abstract OT1-07-06: Phase 1/2 first-in-human study of U3-1402, an anti-human epidermal growth factor receptor 3 (HER3) antibody-drug conjugate, in HER3-expressing advanced/unresectable or metastatic breast cancer, including those with triple negative breast cancer (TNBC) or HER3-low disease
Cancer Research·2020· 2 cited
Hyperglycemia in non‐obese patients with type 2 diabetes is associated with low muscle mass: The Multicenter Study for Clarifying Evidence for Sarcopenia in Patients with Diabetes Mellitus
Journal of Diabetes Investigation·2019· 155 citedOpen Access
Variants in the <i>BACH2</i> and <i>CLEC16A</i> gene might be associated with susceptibility to insulin‐triggered type 1 diabetes
Journal of Diabetes Investigation·2019· 11 citedOpen Access
Abstract PD1-03: Single agent activity of U3-1402, a HER3-targeting antibody-drug conjugate, in HER3-overexpressing metastatic breast cancer: Updated results of a phase 1/2 trial
Cancer Research·2019· 16 cited
膵管内乳頭粘液性腫瘍(IPMN)と糖尿病に関する検討
糖尿病(Web)·2019
Serum Resistin Was Inversely Associated with Physical Activity in the C/C Genotype of SNP-420 in the General Japanese Population—The Toon Genome Study
Diabetes·2018· 2 cited
Single agent activity of U3-1402, a HER3-targeting antibody-drug conjugate, in breast cancer patients: Phase 1 dose escalation study.
Journal of Clinical Oncology·2018· 22 cited
Correlation between global methylation level of peripheral blood leukocytes and serum C reactive protein level modified by MTHFR polymorphism: a cross-sectional study
BMC Cancer·2018· 14 citedOpen Access
Nimotuzumab combined with concurrent chemoradiotherapy in Japanese patients with esophageal cancer: A phase I study
Cancer Science·2017· 19 citedOpen Access
An inverse association between serum resistin levels and n‐3 polyunsaturated fatty acids intake was strongest in the SNP‐420 G/G genotype in the Japanese cohort: The Toon Genome Study
Clinical Endocrinology·2017· 10 cited
Low Heart Rate Variability and Sympathetic Dominance Modifies the Association Between Insulin Resistance and Metabolic Syndrome　― The Toon Health Study ―
Circulation Journal·2017· 28 citedOpen Access
Dual Effects of a RETN Single Nucleotide Polymorphism (SNP) at –420 on Plasma Resistin: Genotype and DNA Methylation
The Journal of Clinical Endocrinology & Metabolism·2016· 14 citedOpen Access
235P Phase 1b study of nimotuzumab in combination with concurrent chemoradiotherapy in Japanese patients with locally advanced esophageal cancer
Annals of Oncology·2016
Genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population
Physiological Genomics·2016· 18 cited
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Frequent Co-authors

Haruhiko Osawa(29), Hideichi Makino(20), Wataru Nishida(15), Yasuharu Tabara(15), Ikki Shimizu(13), Yoshio Kasuga(13), Hideki Nishimura(13), Ritsu Kusama(13), Shoichiro Tsugane(13), Yasunori Takata(13), Shiro Yokoyama(12), Tetsuro Miki(12), Masaaki Ochi(10), Katsuhiko Kohara(10), Ryoichi Kawamura(10), Yasuhisa Fujii(9), Jun Ohashi(9), Motoki Iwasaki(9), Tatsuya Nishimiya(8), Ryuichi Kawamoto(8)