Roger Patient

John Radcliffe Hospital — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

58h-index11.3kcitations257works0.02yr avg
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Research Topics

Zebrafish Biomedical Research Applications(78), Congenital heart defects research(66), Epigenetics and DNA Methylation(31), Pluripotent Stem Cells Research(28), Developmental Biology and Gene Regulation(25)

Publications257 total

LSD1 promotes the egress of hematopoietic stem and progenitor cells into the bloodstream during the endothelial-to-hematopoietic transition
Developmental Biology·2023· 2 citedOpen Access
Three-Dimensional Visualization of Blood and Lymphatic Vessels in the Adult Zebrafish Heart by Chemical Clearing
Methods in molecular biology·2022· 2 cited
Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration
Development·2020· 76 citedOpen Access
Functional Heterogeneity within the Developing Zebrafish Epicardium
Developmental Cell·2020· 81 citedOpen Access
Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis
Communications Biology·2020· 34 citedOpen Access
The roles and controls of GATA factors in blood and cardiac development
IUBMB Life·2019· 38 citedOpen Access
Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration
2019· 11 citedOpen Access
Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium
Nature Communications·2019· 61 citedOpen Access
Gene Regulatory Networks Governing the Generation and Regeneration of Blood
Journal of Computational Biology·2019· 11 citedOpen Access
Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos
Nature Communications·2019· 19 citedOpen Access
Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult haematopoiesis
2019· 1 citedOpen Access
A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells
University of Birmingham Research Portal (University of Birmingham)·2019· 2 citedOpen Access
Functional heterogeneity within the developing zebrafish epicardium
2018· 4 citedOpen Access
<i>Vegfa</i> expression is activated through positive and negative transcriptional regulatory networks controlled by the ETS factor Etv6 <i>in vivo</i>
2018Open Access
New methods for computational decomposition of whole-mount in situ images enable effective curation of a large, highly redundant collection of Xenopus images
PLoS Computational Biology·2018· 1 citedOpen Access
An optimized pipeline for parallel image-based quantification of gene expression and genotyping after <i>in situ</i> hybridization
Biology Open·2018· 26 citedOpen Access
Faculty Opinions recommendation of Multiple origins of embryonic and tadpole myeloid cells in Xenopus laevis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Functional analysis of a Gata2a endothelial enhancer reveals non-redundant roles for Gata2a and Gata2b in haemogenic endothelium programming and generation of haematopoietic stem cells
Experimental Hematology·2017
Embryonic thymopoiesis is initiated by an immune-restricted lympho-myeloid progenitor, independently of notch signaling
Experimental Hematology·2017
Faculty Opinions recommendation of Irf4 Regulates the Choice between T Lymphoid-Primed Progenitor and Myeloid Lineage Fates during Embryogenesis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
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Frequent Co-authors

Adam Rodaway(8), Martin Gering(7), Aldo Ciau‐Uitz(6), Maggie Walmsley(6), Tessa Peterkin(5), Nigel Holder(5), Rui Monteiro(5), Feng Liu(4), Matthew Loose(4), Frank Grosveld(3), Filipa C. Simões(3), Manoussos Koutsourakis(2), An Langeveld(2), Rosa Beddington(2), Berthold Göttgens(2), Anthony R. Green(2), Hannah K. Long(2), Duncan T. Odom(2), Robert J. Klose(2), James C. Smith(2)