Robert Tjian

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

150h-index84.6kcitations479works2.82yr avg
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Research Topics

Genomics and Chromatin Dynamics(202), RNA Research and Splicing(144), RNA and protein synthesis mechanisms(71), CRISPR and Genetic Engineering(65), RNA modifications and cancer(44)

Publications476 total

Modulating MyoD1 dosage activates alternate cell fate beyond myogenic differentiation
2025Open Access
Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes
Molecular Cell·2025· 5 citedOpen Access
Collective unstructured interactions drive chromatin binding of transcription factors
2025· 3 citedOpen Access
Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors
Nature Communications·2025· 3 citedOpen Access
Author response: Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging
2025Open Access
Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging
eLife·2025· 4 citedOpen Access
Surprising Features of Nuclear Receptor Interaction Networks Revealed by Live Cell Single Molecule Imaging
2024Open Access
Author response: Surprising Features of Nuclear Receptor Interaction Networks Revealed by Live Cell Single Molecule Imaging
2024Open Access
Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function
Cell Reports·2024· 9 citedOpen Access
TFEB controls expression of human syncytins during cell-cell fusion.
PubMed·2024· 8 citedOpen Access
High-throughput arrayed imaging-based CRISPR screen reveals novel regulators of cell-cell fusion and hormone secretion
Placenta·2024
Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes
2024· 12 citedOpen Access
Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function
2024· 3 citedOpen Access
Issue Information
Annals of the New York Academy of Sciences·2024Open Access
Assessing the impact of Brd2 depletion on chromatin compartmentalization
2024Open Access
TFEB controls syncytiotrophoblast differentiation
2024· 2 citedOpen Access
Correction: Detecting molecular interactions in live-cell single-molecule imaging with proximity-assisted photoactivation (PAPA)
eLife·2024· 1 citedOpen Access
Single-Molecule Live Imaging of Subunit Interactions and Exchange within Cellular Regulatory Complexes
SSRN Electronic Journal·2024Open Access
p300 is an obligate integrator of combinatorial transcription factor inputs
Molecular Cell·2023· 48 citedOpen Access
Reviewer #1 (Public Review): Surprising Features of Nuclear Receptor Interaction Networks Revealed by Live Cell Single Molecule Imaging
2023Open Access
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Frequent Co-authors

James T. Kadonaga(6), Xavier Darzacq(5), Pamela J. Mitchell(4), William S. Dynan(4), Katherine A. Jones(4), Claudia Cattoglio(4), Arie Admon(3), Wes Lee(2), Stephen P. Bell(2), Dirk Bohmann(2), Timothy J. Bos(2), Peter K. Vogt(2), Michael Levine(2), Michael T. Marr(2), Thomas J. Kelly(2), Shasha Chong(2), Zhe Liu(2), Stephen P. Jackson(2), Nicolas Mermod(2), Bryan D. Lemon(2)