Francesca Stillitano

Utrecht University — Netherlands

Medicine · Health Sciences

24h-index2.7kcitations79works0.02yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(32), Pluripotent Stem Cells Research(19), Cardiomyopathy and Myosin Studies(17), Neuroscience and Neural Engineering(14), Cardiovascular Effects of Exercise(11)

Publications78 total

Setting the stage for cardiomyopathy gene editing trials: a systematic review of isogenic pair use in human induced pluripotent stem cell-derived cardiomyocyte research
European Heart Journal Open·2025Open Access
Modeling MYH11-associated aortic disease using iPSC-derived vascular smooth muscle cells for gene therapy development
European Heart Journal·2025
AAV-mediated gene therapy improves cardiac function in humanized PLN-R14del mice: a preclinical model of PLN-R14del induced cardiomyopathy
European Heart Journal·2025
Generation and characterization of human induced pluripotent stem cell (iPSC) lines from two asymptomatic Greek carriers of the Phospholamban (PLN)-R14del pathogenic variant and a non-carrier relative
Stem Cell Research·2025Open Access
Unraveling the Pathophysiological Mechanisms of Phospholamban R14del Cardiomyopathy: A Comprehensive Overview
Circulation Heart Failure·2025
Ultrafast Volumetric Bioprinting Enables Precise Morphological Control of Perfusable Stem Cell-Derived Microphysiological Endocrine Pancreatic Units
SSRN Electronic Journal·2025Open Access
Generation and characterization of novel induced pluripotent stem cell (iPSC) lines derived from three symptomatic carriers of a pathogenic MYH11 variant and two non-carrier relatives
Stem Cell Research·2024Open Access
Generation and characterization of novel human induced pluripotent stem cell (iPSC) lines originating from five asymptomatic individuals carrying the PLN-R14del pathogenic variant and a non-carrier relative
Stem Cell Research·2023· 5 citedOpen Access
Generation, High-Throughput Screening, and Biobanking of Human-Induced Pluripotent Stem Cell-Derived Cardiac Spheroids
Journal of Visualized Experiments·2023· 1 cited
Generation, High-Throughput Screening, and Biobanking of Human-Induced Pluripotent Stem Cell-Derived Cardiac Spheroids
Journal of Visualized Experiments·2023· 6 citedOpen Access
Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy
International Journal of Molecular Sciences·2023· 12 citedOpen Access
Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts
Metabolism·2022· 10 citedOpen Access
Generation of human induced pluripotent stem cell (iPSC) lines derived from five patients carrying the pathogenic phospholamban-R14del (PLN-R14del) variant and three non-carrier family members
Stem Cell Research·2022· 7 citedOpen Access
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact
Cardiovascular Research·2022· 55 citedOpen Access
Abstract P482: Elucidating And Characterizing The Molecular Mechanistic Role Of Phospholamban L39 Stop In The Pathophysiology Of Cardiomyopathy Using Patient-derived Human Induced Pluripotent Stem Cells And Humanized Knock-in Mouse Model Systems
Circulation Research·2021· 2 cited
Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias
Journal of Personalized Medicine·2021· 24 citedOpen Access
A micromachined force sensing apparatus and method for human engineered cardiac tissue and induced pluripotent stem cell characterization
Sensors and Actuators A Physical·2021· 5 citedOpen Access
Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Caused by Phospholamban R14del Mutation
Circulation·2021· 28 citedOpen Access
Establishing correlation of axial and vertical force of cardiac artificial tissue using a novel micromachined sensor
2020Open Access
Abstract 530: Mechanisms Underlying Phospholamban L39 Stop (PLN L39X) Cardiomyopathy
Circulation Research·2020· 1 cited
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Frequent Co-authors

Roger J. Hajjar(21), Elisabetta Cerbai(16), Alessandro Mugelli(14), Kevin D. Costa(11), Laura Sartiani(10), Jean‐Sébastien Hulot(10), Irene C. Turnbull(10), Ioannis Karakikes(9), Evangelia G. Kranias(9), Silvia Suffredini(6), Delaine K. Ceholski(6), Mathieu Nonnenmacher(5), Joshua Mayourian(5), Jaydev Dave(5), Pieter A. Doevendans(5), Martina Del Lungo(4), Chi‐Wing Kong(4), Jens Hansen(4), Kobra Haghighi(4), Fadi G. Akar(4)