John F. Beeler

Saint Louis University — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index784citations24works2.02yr avg
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Research Topics

Cancer Genomics and Diagnostics(8), Lung Cancer Treatments and Mutations(7), Protein Kinase Regulation and GTPase Signaling(6), Cancer Immunotherapy and Biomarkers(3), Receptor Mechanisms and Signaling(3)

Publications24 total

CDK4/6 inhibition mitigates chemotherapy-induced expansion of TP53-mutant clonal hematopoiesis
Blood·2025· 2 citedOpen Access
New Technologies to Image Tumors
Cancer treatment and research·2020· 5 citedOpen Access
Targeted sequencing of plasma cell-free DNA to predict response to PD1 inhibitors in advanced non-small cell lung cancer
Lung Cancer·2019· 101 citedOpen Access
Targeted sequencing of plasma cell-free DNA to predict response to PD1 inhibitors in advanced non-small cell lung cancer.
Journal of Clinical Oncology·2019· 18 cited
P1.01-46 Circulating Tumor DNA Analysis for Predicting Response to Osimertinib and Disease Progression in EGFR-Mutant Non-Small-Cell Lung Cancer
Journal of Thoracic Oncology·2018· 2 cited
P3.04-02 Early Plasma ctDNA Response Anticipates Clinical Response to First-Line Immunotherapy in Advanced NSCLC
Journal of Thoracic Oncology·2018· 1 citedOpen Access
Abstract 4581: Feasibility of an amplicon-based liquid biopsy for <i>ALK</i> and <i>ROS1</i> fusions in advanced non-small cell lung cancer (NSCLC) patients
Cancer Research·2018· 3 cited
Early trends of ctDNA levels in non-small cell lung cancer patients treated with immunotherapy (CLIP-IT): Pilot study.
Journal of Clinical Oncology·2018· 1 cited
Early prediction of outcomes to PD1 inhibitors in non-small cell lung cancer (NSCLC) using next generation sequencing (NGS) of plasma circulating tumor DNA (ctDNA).
Journal of Clinical Oncology·2018· 5 cited
Amplicon-based next-generation sequencing of plasma cell-free DNA for detection of driver and resistance mutations in advanced non-small cell lung cancer
Annals of Oncology·2018· 133 citedOpen Access
Base5, a versatile, highly integrated high-throughput methylation profiling platform for methylation specific PCR based marker identification applied to colorectal cancer
Clinical Cancer Research·2007
Cloning and characterization of the mouse homolog of the human A6 gene
Gene·1997· 11 cited
A Divalent Metal Ion Binding Site in the Kinase Insert Domain of the .alpha.-Platelet-Derived Growth Factor Receptor Regulates Its Association with SH2 Domains
Biochemistry·1995· 10 cited
Regulation of hepatocyte plasma membrane <i>α</i>1-adrenergic receptors by 4<i>β</i>-phorbol 12-myristate 13-acetate
Biochemical Journal·1995· 13 citedOpen Access
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways.
The EMBO Journal·1994· 190 citedOpen Access
Stimulation of the Platelet-Derived Growth Factor β Receptor Signaling Pathway Activates Protein Kinase C-δ
Molecular and Cellular Biology·1994· 100 citedOpen Access
Prokaryotic expression cloning of a novel human tyrosine kinase.
Molecular and Cellular Biology·1994· 43 citedOpen Access
Prokaryotic Expression Cloning of a Novel Human Tyrosine Kinase
Molecular and Cellular Biology·1994· 14 cited
Comparison of calcium-dependent conformational changes in the N-terminal SH2 domains of p85 and gap defines distinct properties for SH2 domains
Biochemistry·1994· 17 cited
Differences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functions
Journal of Biological Chemistry·1993· 79 citedOpen Access
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Frequent Co-authors

Vincent Plagnol(6), Greg Jones(5), Mohammad A. Heidaran(5), William J. LaRochelle(5), Nicolas Guibert(4), Clive Morris(4), Myriam Delaunay(3), Gilles Favre(3), Anne Pradines(3), Julien Mazières(3), Stuart A. Aaronson(3), Márcio F. Chedid(3), Yuebi Hu(2), Gregory R. Jones(2), Karen Howarth(2), Geoffrey R. Oxnard(2), Jean Mourlanette(2), Isabelle Rouquette(2), Jacalyn H. Pierce(2), Steven R. Tronick(2)