Pascale Moreau

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index2.3kcitations196works1.62yr avg
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Research Topics

Cancer therapeutics and mechanisms(48), Cancer Mechanisms and Therapy(47), Synthesis and biological activity(42), Bioactive Compounds and Antitumor Agents(36), Synthesis and Biological Evaluation(29)

Publications193 total

Synthesis of 1H-Pyrrolo[3,2-g]isoquinoline Derivatives as Ligands Targeting Haspin Kinase
Molecules·2025Open Access
Synthesis od Haspin kinase inhibitors and development of potential PROTACs for application in cancer therapy.
SPIRE - Sciences Po Institutional REpository·2025
Synthesis and biological activity of 1H-pyrrolo[3,2-g]isoquinolines as Haspin kinase inhibitors
Bioorganic & Medicinal Chemistry·2025· 1 citedOpen Access
Liposomes loaded with daunorubicin and an emetine prodrug for improved selective cytotoxicity towards acute myeloid leukaemia cells
International Journal of Pharmaceutics·2024· 5 citedOpen Access
Synthesis and biological activities of diversely substituted indolopyrazolocarbazoles.
SPIRE - Sciences Po Institutional REpository·2024
Synthesis of 1H-pyrrolo[3,2-g]isoquinolines as Haspin inhibitors.
SPIRE - Sciences Po Institutional REpository·2024
Development of new indolopyrazolocarbazoles exhibiting kinase inhibitory potencies and anti-leukemic activities.
SPIRE - Sciences Po Institutional REpository·2024
Improved Synthesis and Preparation of Analogues of a Pain-Relieving Pyridin-2(1H)-one
Synthesis·2024· 1 citedOpen Access
Synthesis, kinase inhibition and anti-leukemic activities of diversely substituted indolopyrazolocarbazoles
European Journal of Medicinal Chemistry·2024· 2 citedOpen Access
The Nitro Group Reshapes the Effects of Pyrido[3,4-g]quinazoline Derivatives on DYRK/CLK Activity and RNA Splicing in Glioblastoma Cells
Cancers·2024· 3 citedOpen Access
Synthesis and biological evaluation of 1H-pyrrolo[3,2–g]isoquinolines
Bioorganic & Medicinal Chemistry·2024· 7 citedOpen Access
Synthesis of diversely substituted pyridin-2(1<i>H</i>)-ones and <i>in vivo</i> evaluation of their anti-allodynic effect on cutaneous inflammatory mechanical allodynia
RSC Medicinal Chemistry·2024Open Access
Synthesis of specific inhibitors of Haspin for potential cancer treatment
SPIRE - Sciences Po Institutional REpository·2023
Synthesis of (2-Aminopyrimidin-4-yl)(pyridin-4-yl)methanone and Derivatives
Synthesis·2023Open Access
Supplementary Figure S1 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia
2023Open Access
Supplementary Figure S1 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia
2023Open Access
Data from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia
2023Open Access
Supplementary Table S1 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia
2023Open Access
Supplementary Table S1 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia
2023Open Access
Supplementary Figure S2 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia
2023Open Access
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Frequent Co-authors

Fabrice Anizon(41), Michelle Prudhomme(21), F Giraud(11), Lionel Nauton(11), Vincent Théry(10), Eric Débiton(8), Martine Sancelme(8), Christian Bailly(8), Doriano Fabbro(7), Rufine Akué‐Gédu(6), Fadoua Bouchikhi(6), Laurent Meijer(5), Danièle Sevère(5), Jean‐François Riou(5), Thomas Meyer(5), Laurent Gavara(5), Emilie Rossignol(4), Mathieu Sassatelli(4), Yannick J. Esvan(4), Virginie Suchaud(4)