Helen M. Duhart

National Center for Toxicological Research — United States

Environmental Science · Physical Sciences

19h-index1.6kcitations30works0.02yr avg
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Research Topics

Heavy Metal Exposure and Toxicity(6), Neuroscience and Neuropharmacology Research(5), Forensic Toxicology and Drug Analysis(4), Prenatal Substance Exposure Effects(4), Parkinson's Disease Mechanisms and Treatments(3)

Publications30 total

Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles
NeuroToxicology·2009· 187 cited
Sensing Neurotransmitter and Protein on Neuron-regeneration Membrane of Nanowires
ECS Meeting Abstracts·2009Open Access
Acrylamide decreased dopamine levels and increased 3-nitrotyrosine (3-NT) levels in PC 12 cells
Neuroscience Letters·2009· 19 cited
Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells
Neurochemistry International·2007· 25 cited
Gene expression profiling of MPP+-treated MN9D cells: A mechanism of toxicity study
NeuroToxicology·2007· 18 cited
l-Carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture
Neuroscience·2006· 54 cited
The Interaction of Manganese Nanoparticles with PC-12 Cells Induces Dopamine Depletion
Toxicological Sciences·2006· 448 citedOpen Access
Cocaine Induces a Differential Dose‐Dependent Alteration in the Expression Profile of Immediate Early Genes, Transcription Factors, and Caspases in PC12 Cells
Annals of the New York Academy of Sciences·2005· 36 cited
A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools
BMC Bioinformatics·2005· 24 citedOpen Access
Selective Alterations of Transcription Factors in MPP+-Induced Neurotoxicity in PC12 Cells
NeuroToxicology·2005· 32 cited
Role of Mitochondrial Dysfunction in Neurotoxicity of MPP:<sup>+</sup>: Partial Protection of PC12 Cells by Acetyl‐l‐Carnitine
Annals of the New York Academy of Sciences·2004· 42 cited
3‐Nitropropionic Acid Inhibition of Succinate Dehydrogenase (Complex II) Activity in Cultured Chinese Hamster Ovary Cells
Annals of the New York Academy of Sciences·2003· 24 cited
Cocaine Induces a Dose‐Dependent Alteration in the Expression of Immediate Early Genes <i>c‐fos</i> and SP‐1 and in Nuclear Factor NF‐κβ in PC12 Cells
Annals of the New York Academy of Sciences·2003· 4 cited
Neuroprotection or neurotoxicity: impact of discontinuous dose-response curves on risk assessment.
PubMed·2003· 1 cited
Neuroprotection or Neurotoxicity
Annals of the New York Academy of Sciences·2003· 1 cited
Methamphetamine‐Induced Dopaminergic Neurotoxicity and Production of Peroxynitrite Are Potentiated in Nerve Growth Factor Differentiated Pheochromocytoma 12 Cells
Annals of the New York Academy of Sciences·2002· 14 cited
Hypothermia enhances bcl-2 expression and protects against oxidative stress-induced cell death in chinese hamster ovary cells
Free Radical Biology and Medicine·2001· 69 cited
Quinolinic acid induces oxidative stress in rat brain synaptosomes
Neuroreport·2001· 145 cited
Effect of manganese on the concentration of amino acids in different regions of the rat brain
Journal of Environmental Science and Health Part B·1999· 56 cited
Transplacental pharmacokinetics of cocaine and benzoylecgonine in plasma and hair of rhesus monkeys
Reproductive Toxicology·1998· 8 cited
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Frequent Co-authors

Syed F. Ali(17), William Slikker(17), Glenn D. Newport(8), Tucker A. Patterson(6), Zbigniew Binienda(6), Merle G. Paule(6), Syed Z. Imam(4), Saber M. Hussain(3), Jianyong Wang(3), George W. Lipe(3), Zengjun Xu(3), John J. Schlager(2), Ashraf Virmani(2), John Skinner(2), M P Gillam(2), Julia Klein(2), Kristen McMartin(2), Gideon Koren(2), Hong Fang(2), Charles M. Fogle(2)