Philipp Hadwiger

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index6.4kcitations77works0.02yr avg
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Research Topics

RNA Interference and Gene Delivery(30), Carbohydrate Chemistry and Synthesis(24), Advanced biosensing and bioanalysis techniques(22), Glycosylation and Glycoproteins Research(11), DNA and Nucleic Acid Chemistry(9)

Publications76 total

Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII
BioFactors·2022· 4 citedOpen Access
DUX4 siRNA Optimization for the Development of an Antibody-Oligonucleotide Conjugate (AOC) for the Treatment of FSHD (P17-13.009)
Neurology·2022· 3 cited
Ligand Conjugated Multimeric siRNAs Enable Enhanced Uptake and Multiplexed Gene Silencing
Nucleic Acid Therapeutics·2019· 21 citedOpen Access
Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods
PLoS ONE·2017· 10 citedOpen Access
DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization
Molecular Therapy — Nucleic Acids·2016· 11 citedOpen Access
Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection
Molecular Therapy·2013· 289 citedOpen Access
Myeloid Differentiation of t(8;21)-positive Leukemic Cells AML1/MTG8 Oncogene Suppression by Small Interfering RNAs Supports
2013
RNAi therapeutics for the treatment of chronic hepatitis B virus infection
International Journal of Infectious Diseases·2012Open Access
Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery
ACS Nano·2012· 127 citedOpen Access
Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides
Journal of Controlled Release·2012· 109 cited
Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing
Molecular Therapy — Nucleic Acids·2012· 117 citedOpen Access
EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway
Oncogene·2011· 162 citedOpen Access
Purification of Small Interfering RNA Using Nondenaturing Anion-Exchange Chromatography
Nucleic Acid Therapeutics·2011· 29 cited
PS2-011. Cytokine induction and growth inhibition of primary human cells expressing TLR3 is observed for long double-stranded RNA, but not siRNA
Cytokine·2011
Festphasen‐basierte Synthese sequenzdefinierter T‐, i‐ und U‐Form‐Polymere für den pDNA‐ und siRNA‐Transfer
Angewandte Chemie·2011· 15 cited
Solid‐Phase Synthesis of Sequence‐Defined T‐, i‐, and U‐Shape Polymers for pDNA and siRNA Delivery
Angewandte Chemie International Edition·2011· 192 cited
Characterization of side reactions during the annealing of small interfering RNAs
Analytical Biochemistry·2011· 23 cited
Unique Gene‐Silencing and Structural Properties of 2′‐Fluoro‐Modified siRNAs
Angewandte Chemie International Edition·2011· 184 cited
Unique Gene‐Silencing and Structural Properties of 2′‐Fluoro‐Modified siRNAs
Angewandte Chemie·2011· 27 cited
2'Fluoro modified RNA octamer fA2U2
2010
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Frequent Co-authors

Hans‐Peter Vornlocher(16), Arnold Stütz(14), Matthias John(10), Tanja M. Wrodnigg(10), Andreas Tauss(8), Muthiah Manoharan(7), Ernst Wagner(7), Akin Akinc(6), Dinah W.Y. Sah(6), Kerstin Jahn‐Hofmann(6), Christian W. Ekhart(6), Martin Fechter(6), Eva Mlaker(6), Klaus Charissé(5), Kallanthottathil G. Rajeev(5), Martin A. Maier(5), Thomas Fröhlich(5), Olaf Heidenreich(5), Rajendra K. Pandey(4), Ingo Röhl(4)