John N. Buchholz

Loma Linda University — United States

Neuroscience · Life Sciences

22h-index1.4kcitations67works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(25), Nitric Oxide and Endothelin Effects(17), Receptor Mechanisms and Signaling(11), Ion channel regulation and function(10), Neuroscience of respiration and sleep(8)

Publications67 total

Aging Alters Cerebrovascular Endothelial GPCR and K+ Channel Function: Divergent Role of Biological Sex
The Journals of Gerontology Series A·2019· 28 citedOpen Access
Alteration of Calcium and Electrical Dynamics in Cerebrovascular Endothelium During Development of Alzheimer's disease
The FASEB Journal·2019· 1 cited
Calcium and Signal Transduction
InTech eBooks·2018· 11 cited
Electrical dynamics of isolated cerebral and skeletal muscle endothelial tubes: Differential roles of G‐protein‐coupled receptors and K<sup>+</sup> channels
Pharmacology Research & Perspectives·2018· 15 citedOpen Access
Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology·2014· 23 citedOpen Access
Cerebral Autoregulation Is Minimally Influenced by the Superior Cervical Ganglion in Two- Week-Old Lambs, and Absent in Preterm Lambs Immediately Following Delivery
PLoS ONE·2013· 8 citedOpen Access
Inhibition of DNA methylation reverses norepinephrine-induced cardiac hypertrophy in rats
Cardiovascular Research·2013· 116 cited
Maternal high-altitude hypoxia and suppression of ryanodine receptor-mediated Ca<sup>2+</sup> sparks in fetal sheep pulmonary arterial myocytes
American Journal of Physiology-Lung Cellular and Molecular Physiology·2012· 17 citedOpen Access
Combined influence of ontogeny and chronic hypoxia on ryanodine receptor function in sheep pulmonary arteries and myocytes
The FASEB Journal·2011
Capsaicin Pre-treatment Provides Neurovascular Protection Against Neonatal Hypoxic-Ischemic Brain Injury in Rats
Acta neurochirurgica. Supplementum·2011· 46 cited
Foetal nicotine exposure causes PKCε gene repression by promoter methylation in rat hearts
Cardiovascular Research·2010· 56 citedOpen Access
Roles of cytosolic Ca<sup>2+</sup>concentration and myofilament Ca<sup>2+</sup>sensitization in age-dependent cerebrovascular myogenic tone
American Journal of Physiology-Heart and Circulatory Physiology·2010· 20 citedOpen Access
In P14 rat middle cerebral arteries relations between myogenic tone and cytosolic Ca++ are enhanced by myofilament Ca++ sensitization and increased Ca++ influx, but attenuated by high proportions of non‐contractile smooth muscle cells.
The FASEB Journal·2010
Maturation and long-term hypoxia alters Ca<sup>2+</sup>-induced Ca<sup>2+</sup>release in sheep cerebrovascular sympathetic neurons
Journal of Applied Physiology·2009· 11 citedOpen Access
Advancing Age Alters the Contribution of Calcium Release From Smooth Endoplasmic Reticulum Stores in Superior Cervical Ganglion Cells
The Journals of Gerontology Series A·2009· 6 citedOpen Access
Enhanced capacitative calcium entry and sarcoplasmic-reticulum calcium storage capacity with advanced age in murine mesenteric arterial smooth muscle cells
Experimental Gerontology·2008· 12 citedOpen Access
MYOGENIC TONE IN JUVENILE RAT MCA IS RESISTANT TO BLOCKADE OF CALCIUM INFLUX AND RELEASE OF INTRACELLULAR CALCIUM
The FASEB Journal·2008
IMPACT OF ADVANCING AGE ON CAFFEINE MEDIATED SENSITIZATION OF CALCIUM RELEASE IN SUPERIOR CERVICAL GANGLION CELLS.
The FASEB Journal·2008
Postnatal maturation attenuates pressure-evoked myogenic tone and stretch-induced increases in Ca<sup>2+</sup>in rat cerebral arteries
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology·2007· 14 cited
Age‐dependent changes in Ca<sup>2+</sup>homeostasis in peripheral neurones: implications for changes in function
Aging Cell·2007· 48 citedOpen Access
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Frequent Co-authors

Sue P. Duckles(22), William J. Pearce(10), Li Zhang(8), William J. Pottorf(7), Henry J. Tsai(7), Erik J. Behringer(5), Conwin K. Vanterpool(4), Daliao Xiao(3), Shelton M. Charles(3), Lawrence D. Longo(3), Sean M. Wilson(3), Man Chen(2), Robert P. Iacono(2), Greg G. Geary(2), A. Strother(2), Md Abdul Hakim(2), Emmanuel N. Mbaku(2), Chiranjib Dasgupta(1), Kangling Zhang(1), Zhice Xu(1)