Irene Michalk

University Hospital Carl Gustav Carus — Germany

Medicine · Health Sciences

13h-index714citations23works0.02yr avg
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Research Topics

CAR-T cell therapy research(18), Monoclonal and Polyclonal Antibodies Research(12), Immunotherapy and Immune Responses(6), Immune Cell Function and Interaction(6), T-cell and B-cell Immunology(5)

Publications23 total

And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling
International Journal of Molecular Sciences·2021· 20 citedOpen Access
Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner
International Journal of Molecular Sciences·2021· 15 citedOpen Access
Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts
Blood Cancer Journal·2015· 44 citedOpen Access
Development of a Bispecific Antibody-Releasing Stem Cell System for the Eradication of Acute Myeloid Leukemia Blasts Via Redirected Immune Effector Cells
Blood·2014· 2 cited
Flexible Antigen-Specific Redirection of Human Regulatory T Cells Via a Novel Universal Chimeric Antigen Receptor System
Blood·2014· 50 cited
Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cells via the TCR Co-Receptor CD8
PLoS ONE·2014· 21 citedOpen Access
Cytotoxic response of human regulatory T cells upon T-cell receptor-mediated activation: a matter of purity
Blood Cancer Journal·2014· 11 citedOpen Access
A Novel Ex Vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells
PLoS ONE·2014· 43 citedOpen Access
TCR/CD3 activation and co-stimulation combined in one T cell retargeting system improve anti-tumor immunity
OncoImmunology·2013· 9 citedOpen Access
Enhancing The Efficacy and Specificity Of Antibody-Based T Cell Retargeting Strategies Against Hematological Malignancies
Blood·2013· 5 cited
Cytotoxic Activity Of Bispecific Antibody-Redirected Human Regulatory T Cells: Fact Or Artifact
Blood·2013
Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: description of a novel modular targeting system
Leukemia·2013· 61 cited
The histone demethylase UTX regulates stem cell migration and hematopoiesis
Blood·2013· 101 cited
Retargeting of regulatory T cells to surface-inducible autoantigen La/SS-B
Journal of Autoimmunity·2013· 64 cited
Redirection of T cells with a first fully humanized bispecific CD33–CD3 antibody efficiently eliminates AML blasts without harming hematopoietic stem cells
Leukemia·2013· 69 cited
Novel Humanized and Highly Efficient Bispecific Antibodies Mediate Killing of Prostate Stem Cell Antigen-Expressing Tumor Cells by CD8+ and CD4+ T Cells
The Journal of Immunology·2012· 98 cited
Cancer Immunotherapy by Retargeting of Immune Effector Cells via Recombinant Bispecific Antibody Constructs
Antibodies·2012· 30 citedOpen Access
Isolation of Proteins from Polyacrylamide Gels
Methods in molecular biology·2012· 3 cited
Gel Drying Methods
Methods in molecular biology·2012· 5 cited
Retargeting of Human Regulatory T Cells by Single-Chain Bispecific Antibodies
The Journal of Immunology·2011· 50 cited
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Frequent Co-authors

Michael Bachmann(23), Claudia Arndt(21), Anja Feldmann(20), Stefanie Koristka(19), Marc Cartellieri(18), Gerhard Ehninger(17), Martin Bornhäuser(15), Slava Stamova(11), Marc Schmitz(11), Malte von Bonin(8), Nicole Berndt(5), Katrin Töpfer(4), Achim Temme(4), Claudia C. Bippes(4), Roberta Aliperta(4), Armin Ehninger(4), Dirk Lindemann(3), A Gocht(2), Anke Theil(2), Karsten Kretschmer(2)