Aike A. Kruize

Utrecht University — Netherlands

Medicine · Health Sciences

34h-index5.7kcitations158works32.02yr avg
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Research Topics

Salivary Gland Disorders and Functions(104), Salivary Gland Tumors Diagnosis and Treatment(31), Systemic Lupus Erythematosus Research(28), Systemic Sclerosis and Related Diseases(17), Oral Health Pathology and Treatment(15)

Publications157 total

2023 International Rome consensus for the nomenclature of Sjögren disease
Nature Reviews Rheumatology·2025· 32 citedOpen Access
Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren’s syndrome that show potential to predict and monitor clinical response
RMD Open·2023· 10 citedOpen Access
CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren’s Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells
International Journal of Molecular Sciences·2023· 11 citedOpen Access
POS0814 UNTARGETED METABOLOMICS ANALYSIS OF SEBUM: A NON-INVASIVE STRATEGY THAT SHOWS POTENTIAL TO IDENTIFY NEW BIOMARKERS IN PRIMARY SJÖGREN’S SYNDROME AND SYSTEMIC SCLEROSIS
2023· 1 citedOpen Access
In patients with primary Sjögren’s syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells
Frontiers in Immunology·2022· 15 citedOpen Access
Deciphering the role of cDC2s in Sjögren's syndrome: transcriptomic profile links altered antigen processes with IFN signature and autoimmunity
Annals of the Rheumatic Diseases·2022· 20 citedOpen Access
CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren’s Syndrome
Frontiers in Immunology·2022· 18 citedOpen Access
Characterization and outcomes of 414 patients with primary SS who developed haematological malignancies
Lara D. Veeken·2022· 28 citedOpen Access
Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium.
PubMed·2021· 16 cited
Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium
Clinical and Experimental Rheumatology·2021· 38 citedOpen Access
The Transcriptomic Profile of Monocytes from Patients With Sjögren’s Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators
Frontiers in Immunology·2021· 23 citedOpen Access
Transcriptome Analysis of CCR9+ T Helper Cells From Primary Sjögren’s Syndrome Patients Identifies CCL5 as a Novel Effector Molecule
Frontiers in Immunology·2021· 14 citedOpen Access
Therapeutic Recommendations for the Management of Older Adult Patients with Sjögren’s Syndrome
Drugs & Aging·2021· 11 citedOpen Access
Childhood-onset of primary Sjögren’s syndrome: phenotypic characterization at diagnosis of 158 children
Lara D. Veeken·2021· 63 citedOpen Access
Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium
University of Groningen research database (University of Groningen / Centre for Information Technology)·2021Open Access
Systemic phenotype related to primary Sjögren's syndrome in 279 patients carrying isolated anti-La/SSB antibodies.
PubMed·2020· 15 cited
SARS-CoV-2 infection in patients with primary Sjögren syndrome: characterization and outcomes of 51 patients
Lara D. Veeken·2020· 20 citedOpen Access
Childhood-onset of primary Sjogren syndrome Phenotypic characterization at diagnosis of 158 children
2020· 4 citedOpen Access
Leflunomide–hydroxychloroquine combination therapy in patients with primary Sjögren's syndrome (RepurpSS-I): a placebo-controlled, double-blinded, randomised clinical trial
The Lancet Rheumatology·2020· 81 cited
Epidemiological profile and north–south gradient driving baseline systemic involvement of primary Sjögren’s syndrome
Lara D. Veeken·2019· 83 citedOpen Access
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Frequent Co-authors

Manuel Ramos‐Casals(14), Hendrika Bootsma(13), Raphaèle Séror(13), Joël A. G. van Roon(13), Pilar Brito‐Zerón(12), Thomas Mandl(12), Stefano Bombardieri(12), J. W. J. Bijlsma(12), Salvatore De Vita(9), Gabriela Hernández‐Molina(9), Wan‐Fai Ng(9), Soledad Retamozo(9), Sonja Praprotnik(9), Valéria Valim(9), Chiara Baldini(9), Jacques‐Eric Gottenberg(8), Thomas Dörner(7), Athanasios G. Tzioufas(7), Simon Bowman(7), Xavier Mariette(7)