Patricio Aller

Consejo Superior de Investigaciones Científicas — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index2.8kcitations91works0.02yr avg
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Research Topics

Retinoids in leukemia and cellular processes(17), Cell death mechanisms and regulation(14), Heat shock proteins research(11), NF-κB Signaling Pathways(10), Cancer therapeutics and mechanisms(8)

Publications91 total

Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activation
Oncology Reports·2018· 42 citedOpen Access
Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities
Cancer Cell International·2016· 21 citedOpen Access
Apoptotic Efficacy of Etomoxir in Human Acute Myeloid Leukemia Cells. Cooperation with Arsenic Trioxide and Glycolytic Inhibitors, and Regulation by Oxidative Stress and Protein Kinase Activities
PLoS ONE·2014· 42 citedOpen Access
Mechanisms of resistance to apoptosis in the human acute promyelocytic leukemia cell line NB4
Annals of Hematology·2014· 8 cited
Chemosensitization of tumor cells using drugs that affect the cellular energy metabolism
Biochimica et Biophysica Acta (BBA) - Bioenergetics·2014
Regulation of Death Induction and Chemosensitizing Action of 3-Bromopyruvate in Myeloid Leukemia Cells: Energy Depletion, Oxidative Stress, and Protein Kinase Activity Modulation
Journal of Pharmacology and Experimental Therapeutics·2013· 36 cited
2-Deoxy-d-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: Involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways
Biochemical Pharmacology·2012· 43 citedOpen Access
Identification of virtual signal transducers and activators of transcription response elements in the human insulin receptor gene promoter
Computational Biology and Chemistry·2011· 1 cited
Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation
Biochemical Pharmacology·2011· 52 cited
Expression of NF‐κB‐related proteins and their modulation during TNF‐α‐provoked apoptosis in prostate cancer cells
The Prostate·2011· 18 cited
Development of Chromanes as Novel Inhibitors of the Uncoupling Proteins
Chemistry & Biology·2011· 25 cited
Arsenic trioxide as an anti-tumour agent: mechanisms of action and strategies of sensitization
Journal of Applied Biomedicine·2010· 11 citedOpen Access
Curcumin Stimulates Reactive Oxygen Species Production and Potentiates Apoptosis Induction by the Antitumor Drugs Arsenic Trioxide and Lonidamine in Human Myeloid Leukemia Cell Lines
Journal of Pharmacology and Experimental Therapeutics·2010· 83 cited
Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases
Chemico-Biological Interactions·2009· 28 citedOpen Access
Inhibition of p38-MAPK Potentiates Cisplatin-Induced Apoptosis via GSH Depletion and Increases Intracellular Drug Accumulation in Growth-Arrested Kidney Tubular Epithelial Cells
Toxicological Sciences·2009· 30 citedOpen Access
Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4)
Biochemical Pharmacology·2008· 56 citedOpen Access
Genistein selectively potentiates arsenic trioxide‐induced apoptosis in human leukemia cells <i>via</i> reactive oxygen species generation and activation of reactive oxygen species‐inducible protein kinases (p38‐MAPK, AMPK)
International Journal of Cancer·2008· 73 cited
Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines
Biochemical Pharmacology·2008· 93 cited
Arsenic trioxide sensitizes promonocytic leukemia cells to TNFα-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2007· 21 cited
P38 MAPK protects against TNF-α-provoked apoptosis in LNCaP prostatic cancer cells
APOPTOSIS·2006· 47 cited
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Frequent Co-authors

Elena de Blas(29), Nuria Vilaboa(12), Carlos Fernández(9), Laura García‐Bermejo(8), Alfonso Troyano(7), Patricia Sancho(7), Adrián M. Ramos(7), Donna Amrán(7), Carlos Rı́us(6), F. Mata(6), Concepción Pérez(6), Consuelo Calle(6), Yolanda Sánchez(5), Eva Calviño(5), María Cristina Estañ(5), Marı́a del Carmen Boyano-Adánez(5), Alba Galán(4), Carlos Cabañas(4), Eduardo Rial(4), Carlos Fernández(3)