Duncan Sousa

Johns Hopkins University — United States

Medicine · Health Sciences

15h-index740citations30works1.02yr avg
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Research Topics

Cardiomyopathy and Myosin Studies(10), Virus-based gene therapy research(9), Cardiovascular Effects of Exercise(7), RNA and protein synthesis mechanisms(5), Viral Infections and Immunology Research(5)

Publications30 total

The hypertrophic cardiomyopathy-associated A331P actin variant enhances basal contractile activity and elicits resting muscle dysfunction
iScience·2025· 1 citedOpen Access
Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity
Journal of Virology·2022· 19 citedOpen Access
The ACTC A331P hypertrophic cardiomyopathy mutation enhances basal contractile activity and causes resting muscle dysfunction
Biophysical Journal·2022
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2
Journal of Structural Biology·2021· 8 citedOpen Access
pH-Induced Conformational Changes of Human Bocavirus Capsids
Journal of Virology·2021· 10 citedOpen Access
Yeast R2TP Interacts with Extended Termini of Client Protein Nop58p
Scientific Reports·2019· 7 citedOpen Access
Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2
Journal of Structural Biology·2019· 33 citedOpen Access
Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8
Journal of Virology·2019· 67 citedOpen Access
Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue
Molecular Therapy·2019· 46 citedOpen Access
Structural Characterization of Emerging Pathogenic Human Parvoviruses
Microscopy and Microanalysis·2018· 2 citedOpen Access
Atomic structure of a rationally engineered gene delivery vector, AAV2.5
Journal of Structural Biology·2018· 30 citedOpen Access
Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy
Viruses·2018· 25 citedOpen Access
Structural Insights into Human Bocaparvoviruses
Journal of Virology·2017· 52 citedOpen Access
Mechanism of ribosome rescue by ArfA and RF2
eLife·2017· 60 citedOpen Access
The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide
Molecular Therapy — Methods & Clinical Development·2017· 35 citedOpen Access
Author response: Mechanism of ribosome rescue by ArfA and RF2
2017· 3 citedOpen Access
Mechanism of ribosome rescue by ArfA and RF2
2016· 1 citedOpen Access
The influence of frame alignment with dose compensation on the quality of single particle reconstructions
Journal of Structural Biology·2015· 31 citedOpen Access
The structure of Sinorhizobium meliloti phage ΦM12, which has a novel T=19l triangulation number and is the founder of a new group of T4-superfamily phages
Virology·2014· 16 cited
Cryo-Em Structures of the Actin:Tropomyosin Filament Reveal the Mechanism for the Transition from C- to M-State
Biophysical Journal·2014Open Access
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Frequent Co-authors

Mavis Agbandje‐McKenna(9), William Lehman(9), Mario Mietzsch(8), Paul R. Chipman(8), Robert McKenna(8), John Spear(6), Nikolaus Grigorieff(5), Antonette Bennett(5), Scott M. Stagg(5), Maria Söderlund‐Venermo(4), Anthony Cammarato(4), Xiaochuan Li(4), Joshua A. Hull(3), Nilakshee Bhattacharya(3), Gabriel Demo(3), E. Svidritskiy(3), Rohini Madireddy(3), Rubén Díaz-Avalos(3), Timothy Grant(3), А.A. Коростелев(3)