Savvas Christoforidis

University of Ioannina — Greece

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index5.9kcitations51works2.02yr avg
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Research Topics

Cellular transport and secretion(25), Retinal Development and Disorders(8), Microtubule and mitosis dynamics(5), PI3K/AKT/mTOR signaling in cancer(5), Pancreatic function and diabetes(4)

Publications51 total

A new functional assay reveals that membrane binding is critical for overactivation of the phosphoinositide 3-kinase H1047R mutant
Journal of Biological Chemistry·2026Open Access
Developing MYC Degraders Bearing the Von Hippel–Lindau Ligand to Target the “Undruggable” MYC
ACS Pharmacology & Translational Science·2024· 4 citedOpen Access
The Rab5 effector FERRY links early endosomes with mRNA localization
Molecular Cell·2023· 56 citedOpen Access
The orchestrated signaling by PI3Kα and PTEN at the membrane interface
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
The orchestrated signaling by PI3Kα and PTEN at the membrane interface
Computational and Structural Biotechnology Journal·2022· 14 citedOpen Access
Fabricating a Low-cost and Low-immune Xenogeneic Aortic Valve Bio Prosthesis
2021Open Access
Intracellular targets: A multiple cargo transporting molecule
Journal of Peptide Science·2021· 7 cited
Chemical Inhibitors of Dynamin Exert Differential Effects in VEGF Signaling
Cells·2021· 17 citedOpen Access
The Novel Rab5 Effector FERRY Links Early Endosomes With the Translation Machinery
SSRN Electronic Journal·2021· 9 citedOpen Access
Abstract 3918: Νovel small molecule modulators of the hotspot PIK3CA mutants identified by computational and experimental approaches
Experimental and Molecular Therapeutics·2019
Abstract 3918: Νovel small molecule modulators of the hotspot PIK3CA mutants identified by computational and experimental approaches
Cancer Research·2019
Dynasore impairs VEGFR2 signalling in an endocytosis-independent manner
Scientific Reports·2017· 40 citedOpen Access
Discovery of New Aminosubstituted Pyrrolopyrimidines with Antiproliferative Activity Against Breast Cancer Cells and Investigation of their Effect Towards the PI3Kα Enzyme
Anti-Cancer Agents in Medicinal Chemistry·2017· 4 cited
The AP-2 complex has a specialized clathrin-independent role in apical endocytosis and polar growth in fungi
eLife·2017· 58 citedOpen Access
Design and synthesis of novel 7-aminosubstituted pyrido[2,3-b]pyrazines exhibiting anti-breast cancer activity
European Journal of Medicinal Chemistry·2016· 22 citedOpen Access
VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis
Development·2016· 3 cited
Author response: The AP-2 complex has a specialized clathrin-independent role in apical endocytosis and polar growth in fungi
2016· 1 citedOpen Access
VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis
Journal of Cell Science·2016· 112 citedOpen Access
Constitutive Endocytosis of VEGFR2 Protects the Receptor against Shedding
Journal of Biological Chemistry·2016· 54 citedOpen Access
Proteome Changes during Transition from Human Embryonic to Vascular Progenitor Cells
Journal of Proteome Research·2016· 8 citedOpen Access
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Frequent Co-authors

Marino Zerial(15), Alexandra Papafotika(10), Matthias Wilm(8), Sandrine Uttenweiler‐Joseph(7), Dimitris Basagiannis(7), Sofia Zografou(7), Zoe Cournia(6), Carol Murphy(5), Thomais Papamarcaki(4), Constantin Tamvakopoulos(4), Marta Miączyńska(3), Angelika Giner(3), Theodore Fotsis(3), Paraskevi Gkeka(3), Maria Pavlaki(3), Vasiliki Lazani(3), Bogos Agianian(3), Orestes Tsolas(3), Evangelos Kolettas(3), Orestis Argyros(3)