Lofton Hava

The University of Texas Health Science Center at Tyler — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index390citations17works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Bacterial Genetics and Biotechnology(6), Tuberculosis Research and Epidemiology(5), Synthesis and Reactivity of Sulfur-Containing Compounds(4), Synthesis and biological activity(3), Synthesis and Characterization of Heterocyclic Compounds(3)

Publications17 total

<i>Mtb</i> H<sub>37</sub>Rv and BJ cell data of benzothiazolyl Sulindac amide derivatives 38–43.
Figshare·2016Open Access
Synthetic pathways to analogs 18–43.
Figshare·2016Open Access
Synthetic pathways to analogs 56–57.
Figshare·2016Open Access
<i>Mtb</i> H<sub>37</sub>Rv and BJ cell data of α-methyl Sulindac sulfide amide derivatives 44–55.
Figshare·2016Open Access
<i>Mtb</i> H<sub>37</sub>Rv and BJ cell data of extended Sulindac sulfide amide derivatives 56–57.
Figshare·2016Open Access
Whole cell activity of three E-conformers 61–63.
Figshare·2016Open Access
<i>Mtb</i> H<sub>37</sub>Rv and BJ cell data of Sulindac sulfide amide derivatives 18–37.
Figshare·2016Open Access
Structures of a diverse set of compounds selected for screening.
Figshare·2016Open Access
<i>Mtb</i> H<sub>37</sub>Rv and BJ cell data of Sulindac sulfide amine derivatives 58–60.
Figshare·2016Open Access
Compounds 62 and 63 inhibit FtsZ ring assembly and growth of <i>M</i>.<i>tuberculosis</i>.
Figshare·2016Open Access
Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis
PLoS ONE·2016· 25 citedOpen Access
ChiZ levels modulate cell division process in mycobacteria
Tuberculosis·2011· 28 cited
Mycobacterium tuberculosis ftsZ expression and minimal promoter activity
Tuberculosis·2009· 15 cited
Interference of <i>Mycobacterium tuberculosis</i> cell division by Rv2719c, a cell wall hydrolase
Molecular Microbiology·2006· 120 cited
<i>Mycobacterium tuberculosis</i> Cells Growing in Macrophages Are Filamentous and Deficient in FtsZ Rings
Journal of Bacteriology·2006· 131 citedOpen Access
Genetic evidence that mycobacterial FtsZ and FtsW proteins interact, and colocalize to the division site in<i>Mycobacterium smegmatis</i>
FEMS Microbiology Letters·2005· 40 cited
Mutations in the GTP-binding and synergy loop domains of Mycobacterium tuberculosis ftsZ compromise its function in vitro and in vivo
Biochemical and Biophysical Research Communications·2005· 31 cited

Frequent Co-authors

Bini Mathew(11), Hobrath Judith Varady(10), Ross Larry(10), Connelly Michele C.(10), Rajagopalan Malini(10), Guy R. Kiplin(10), Reynolds Robert C.(10), Malini Rajagopalan(7), Murty V. Madiraju(6), Ashwini Chauhan(5), Erin A. Maloney(4), Marek Fol(2), Robert C. Reynolds(2), Jacob D. Moore(1), Jarosław Dziadek(1), Marta Popławska(1), Mark A. Atkinson(1), Indumathi S. Vadrevu(1), Krishna Sarva(1), Ewelina Blasczyk(1)