Martin J. Simard

Université Laval — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index6.1kcitations75works2.32yr avg
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Research Topics

MicroRNA in disease regulation(40), RNA Research and Splicing(31), Genetics, Aging, and Longevity in Model Organisms(21), RNA modifications and cancer(16), CRISPR and Genetic Engineering(13)

Publications75 total

DAF-18/PTEN prevents oocyte wastage in spermless <i>C. elegans</i> hermaphrodites by blocking spermatheca neck dilation through RHO-1/RhoA disinhibition
2025Open Access
CSDE1 promotes passenger strand cleavage of miR-486
2025Open Access
Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals
Nature Communications·2025· 7 citedOpen Access
Interaction between a J-domain co-chaperone and a specific Argonaute protein contributes to microRNA function in animals
Nucleic Acids Research·2024· 2 citedOpen Access
Defining the contribution of microRNA-specific Argonautes with slicer capability in animals
Nucleic Acids Research·2024· 5 citedOpen Access
Interaction between a J-domain co-chaperone and a specific Argonaute protein contributes to microRNA function in animals
2024Open Access
Casein kinase 1 and 2 phosphorylate Argonaute proteins to regulate <scp>miRNA</scp> ‐mediated gene silencing
EMBO Reports·2023· 16 citedOpen Access
CSDE1 promotes miR-451 biogenesis
Nucleic Acids Research·2023· 12 citedOpen Access
Defining the contribution of microRNA-specific slicing Argonautes in animals
2023· 1 citedOpen Access
A specific type of Argonaute phosphorylation regulates binding to microRNAs during C. elegans development
Cell Reports·2022· 18 citedOpen Access
Regulation and different functions of the animal microRNA‐induced silencing complex
Wiley Interdisciplinary Reviews - RNA·2021· 48 cited
CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma
Oncogene·2021· 20 cited
The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans
PLoS Genetics·2021· 7 citedOpen Access
CSDE1 controls gene expression through the miRNA-mediated decay machinery
Life Science Alliance·2020· 26 citedOpen Access
Defend Thyself and Thy Offspring
Developmental Cell·2019· 1 citedOpen Access
A guide to micro<scp>RNA</scp>‐mediated gene silencing
FEBS Journal·2018· 65 citedOpen Access
Somatic and Germline MicroRNAs Form Distinct Silencing Complexes to Regulate Their Target mRNAs Differently
Developmental Cell·2018· 68 citedOpen Access
Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation
The FASEB Journal·2018· 201 cited
La biogenèse des ARN courts non codants chez les animaux
médecine/sciences·2018· 7 citedOpen Access
p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells
Scientific Reports·2018· 38 citedOpen Access
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Frequent Co-authors

Guillaume Jannot(11), Éric R. Paquet(8), Jacques Huot(5), Miguel Quévillon Huberdeau(5), François Houle(5), Alejandro Vasquez-Rifo(5), Benoı̂t Chabot(5), Alexandra Dallaire(5), György Hutvàgner(4), Samir Bouasker(4), Sandra Piquet(4), Gabriel D. Bossé(4), Craig C. Mello(3), Nellie J. Giguère(3), Eric A. Miska(3), Liang Zhong(3), Astrid Bruckmann(3), Gunter Meister(3), Evelyne L. Rondeau(3), Chun-Chieh G. Chen(2)