Mike D. Barker

Chemistry · Physical Sciences

7h-index225citations14works1.02yr avg
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Research Topics

Asymmetric Synthesis and Catalysis(4), Asymmetric Hydrogenation and Catalysis(4), Synthetic Organic Chemistry Methods(3), Coordination Chemistry and Organometallics(3), Inflammatory mediators and NSAID effects(2)

Publications14 total

Phenotype-Led Identification of IL-10 Upregulators in Human CD4<sup>+</sup> T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors
Journal of Medicinal Chemistry·2025· 1 cited
GSK2646264, a spleen tyrosine kinase inhibitor, attenuates the release of histamine in ex vivo human skin
British Journal of Pharmacology·2019· 27 citedOpen Access
Enantioselective Catalytic Desymmetrization of Maleimides by Temporary Removal of an Internal Mirror Plane and Stereoablative Over-reduction: Synthesis of (<i>R</i>)-Pyrrolam A
Organic Letters·2014· 23 citedOpen Access
CCDC 994911: Experimental Crystal Structure Determination
The Cambridge Structural Database·2014Open Access
CCDC 994912: Experimental Crystal Structure Determination
The Cambridge Structural Database·2014Open Access
Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors
SLAS DISCOVERY·2012· 20 citedOpen Access
ChemInform Abstract: Kinetic Resolution of Racemic Pyrrolidine‐2,5‐diones Using Chiral Oxazaborolidine Catalysts.
ChemInform·2008
Kinetic resolution of racemic pyrrolidine-2,5-diones using chiral oxazaborolidine catalysts
Chemical Communications·2008· 11 cited
Carbon—Carbon Bond Forming Reactions with Substrates Absorbed Non‐Covalently on a Cellulose Chromatography Paper Support.
ChemInform·2007
The Crucial Role of the Nitrogen Substituent in the Desymmetrization of Cyclic meso‐Imides Using B‐Me and B‐O‐Me Oxazaborolidine Catalysts.
ChemInform·2007
Carbon–carbon bond forming reactions with substrates absorbed non-covalently on a cellulose chromatography paper support
Chemical Communications·2006· 4 cited
The crucial role of the nitrogen substituent in the desymmetrisation of cyclic meso-imides using B-Me and B-OMe oxazaborolidine catalysts
Tetrahedron·2006· 18 cited
Dissociated Nonsteroidal Glucocorticoid Receptor Modulators; Discovery of the Agonist Trigger in a Tetrahydronaphthalene−Benzoxazine Series
Journal of Medicinal Chemistry·2006· 77 citedOpen Access
Design and Synthesis of New Nonsteroidal Glucocorticoid Modulators through Application of an “Agreement Docking” Method
Journal of Medicinal Chemistry·2005· 44 citedOpen Access

Frequent Co-authors

Barrie J. Marsh(7), Simon Jones(7), Michael J. Johnston(4), Stephen E. Shanahan(4), Simon J. F. Macdonald(4), Rachel Dixon(4), Graham G. A. Inglis(3), Harry Adams(3), Ibrahim U. Kutama(3), Margaret Clackers(2), Derek A. Demaine(2), Davina Humphreys(2), Haydn T. Jones(2), François Pacquet(2), Philip A. Skone(2), V. Vinader(2), Iain Uings(2), Iain M. McLay(2), Jonathon Hacon(2), Amanda Morris(2)