Matthew T. Jenkins

Vanderbilt University Medical Center — United States

Medicine · Health Sciences

10h-index346citations26works7.52yr avg
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Research Topics

Acute Myeloid Leukemia Research(11), Neuroscience and Neuropharmacology Research(5), Receptor Mechanisms and Signaling(5), Myeloproliferative Neoplasms: Diagnosis and Treatment(5), Epigenetics and DNA Methylation(4)

Publications26 total

TET2 loss enhances early response to inflammation in primitive and committed myeloid cells
Experimental Hematology·2026
Mutant calreticulin–directed immunotherapies in myeloproliferative neoplasms
Blood Neoplasia·2026Open Access
TET2-loss enhances immediate and time-resolved interferon-γ signaling responses across myeloid differentiation
Experimental Hematology·2025· 4 citedOpen Access
Combined Human and In Vivo Analyses Implicate the Critical Importance of Acute Myeloid Leukemia Associated CD8 T Cells and Identifies Their Molecular Dysfunction
Blood·2024
In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy
Cancer Cell·2024· 9 citedOpen Access
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation
Blood Advances·2024· 32 citedOpen Access
Evaluation of oncology infusion pharmacy practices: A nationwide survey
Journal of Oncology Pharmacy Practice·2023· 1 cited
Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation
2022· 8 citedOpen Access
Epigenetic Dysregulation Leads to Enhanced IL-1β Signaling and Transcriptional Responses in <i>TET2</i> Deficient HSPCs
Blood·2022· 1 cited
Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in <i>TET2</i> Clonal Hematopoiesis of Indeterminate Potential
Blood·2022
Development and profiling of mGlu7 NAMs with a range of saturable inhibition of agonist responses in vitro
Bioorganic & Medicinal Chemistry Letters·2022· 3 citedOpen Access
ASHP Statement on Telehealth Pharmacy Practice
American Journal of Health-System Pharmacy·2022· 11 cited
Modeling clonal evolution and oncogenic dependency in vivo in the context of hematopoietic transformation
2022· 2 citedOpen Access
Development and Profiling of mGlu &lt;sub&gt;7&lt;/sub&gt; NAMs with a Range of &lt;i&gt;in vitro&lt;/i&gt; Efficacies
SSRN Electronic Journal·2022Open Access
Isocitrate dehydrogenase mutations are associated with altered IL-1β responses in acute myeloid leukemia
Leukemia·2021· 11 citedOpen Access
Multi-Recombinase Mouse Models of Flt3-Driven Leukemia Identifies Distinct Trajectories of Mutational Cooperativity and Leukemic Transformation
Blood·2021
The delta isoform of phosphatidylinositol-3-kinase predominates in chronic myelomonocytic leukemia and can be targeted effectively with umbralisib and ruxolitinib
Experimental Hematology·2021· 7 citedOpen Access
Synthesis and SAR of a series of mGlu7 NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core
Bioorganic & Medicinal Chemistry Letters·2020· 8 citedOpen Access
Phenotypic profiling of <scp>mGlu<sub>7</sub></scp> knockout mice reveals new implications for neurodevelopmental disorders
Genes Brain & Behavior·2020· 33 citedOpen Access
Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M4 positive allosteric modulator (PAM) chemotype
Bioorganic & Medicinal Chemistry Letters·2019· 9 citedOpen Access
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Frequent Co-authors

Chad R. Potts(9), P. Brent Ferrell(9), Craig W. Lindsley(8), Colleen M. Niswender(8), Alice L. Rodriguez(7), P. Jeffrey Conn(6), Carson W. Reed(5), Anna L. Blobaum(5), Pawan Bhat(4), Michael R. Savona(4), Darren W. Engers(4), Sichen Chang(4), Robert S. Welner(4), Robert L. Bowman(4), Ross L. Levine(4), J. Brett Heimlich(3), Alyssa Parker(3), Jessica Ulloa(3), Alexander J. Silver(3), Donovan Brown(3)