Torleif Härd

Swedish University of Agricultural Sciences — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

45h-index7.1kcitations180works0.02yr avg
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Research Topics

Protein Structure and Dynamics(37), DNA and Nucleic Acid Chemistry(34), Alzheimer's disease research and treatments(31), Monoclonal and Polyclonal Antibodies Research(24), RNA and protein synthesis mechanisms(20)

Publications180 total

Enhanced detection of ATTR amyloid using a nanofibril-based assay
Amyloid·2021· 4 citedOpen Access
Coupled chemistry kinetics demonstrate the utility of functionalized Sup35 amyloid nanofibrils in biocatalytic cascades
Journal of Biological Chemistry·2019· 9 citedOpen Access
Affibody-Mediated Sequestration of Amyloid β Demonstrates Preventive Efficacy in a Transgenic Alzheimer’s Disease Mouse Model
Frontiers in Aging Neuroscience·2019· 26 citedOpen Access
Protofibrillar and Fibrillar Amyloid-β Binding Proteins in Cerebrospinal Fluid
Journal of Alzheimer s Disease·2018· 9 cited
Production of Ready-To-Use Functionalized Sup35 Nanofibrils Secreted by <i>Komagataella pastoris</i>
ACS Nano·2018· 7 cited
The kinetics of TEM1 antibiotic degrading enzymes that are displayed on Ure2 protein nanofibrils in a flow reactor
PLoS ONE·2018· 3 citedOpen Access
Identification of proteins that specifically recognize and bind protofibrillar aggregates of amyloid-β
Scientific Reports·2017· 20 citedOpen Access
[P1–229]: AMYLOID β‐BINDING PROTEINS IN HUMAN BIOLOGICAL FLUID: A COMPARISON BETWEEN PROTOFIBRILS AND FIBRIL BINDERS
Alzheimer s & Dementia·2017
A fine‐tuned composition of protein nanofibrils yields an upgraded functionality of displayed antibody binding domains
Biotechnology Journal·2017· 9 cited
Combined Solution‐ and Magic Angle Spinning NMR Reveals Regions of Distinct Dynamics in Amyloid β Protofibrils
ChemistrySelect·2016· 4 cited
Structural basis for Myf and Psa fimbriae‐mediated tropism of pathogenic strains of <i>Yersinia</i> for host tissues
Molecular Microbiology·2016· 17 citedOpen Access
P3‐050: An Affibody to Monomeric Aβ as a Novel Therapeutic Approach for Alzheimer's Disease Pathology
Alzheimer s & Dementia·2016· 1 cited
A truncated and dimeric format of an Affibody library on bacteria enables FACS‐mediated isolation of amyloid‐beta aggregation inhibitors with subnanomolar affinity
Biotechnology Journal·2015· 39 citedOpen Access
Contact between the β1 and β2 Segments of α‐Synuclein that Inhibits Amyloid Formation
Angewandte Chemie International Edition·2015· 29 cited
Kontakt zwischen den β1‐ und β2‐Segmenten von α‐Synuclein inhibiert die Amyloidbildung
Angewandte Chemie·2015· 5 cited
Affibody-mediated Reduction of Amyloid Burden and Improvement of Cognitive Decline in an Animal Model of Alzheimer’s disease
2015
Selection of binding proteins that specifically recognize protofibrillar aggregates of amyloid-β
2015
A β‐Hairpin‐Binding Protein for Three Different Disease‐Related Amyloidogenic Proteins
ChemBioChem·2014· 27 cited
Binding of Human Proteins to Amyloid-β Protofibrils
ACS Chemical Biology·2014· 35 cited
A Hexameric Peptide Barrel as Building Block of Amyloid‐β Protofibrils
Angewandte Chemie·2014· 8 cited
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Frequent Co-authors

H. Berglund(8), Christofer Lendel(7), Bertil Macao(6), Thomas Lundbäck(6), Jan-Ακε Gustafsson(5), Anders Sandberg(5), Anatoly Dubnovitsky(5), Herbert Baumann(5), Peter Allard(5), Wolfgang Hoyer(4), Christopher M. Dobson(4), Stefan Knapp(4), Rudolf Ladenstein(4), Magnus Helgstrand(4), Leila M. Luheshi(3), Teresa P. Barros(3), M. Hammarstrom(3), Susanne van den Berg(3), Anthony P. H. Wright(3), Henrik Hansson(3)