Konrad Gabrusiewicz

Cell Medica (Switzerland) — Switzerland

Immunology and Microbiology · Life Sciences

29h-index7.9kcitations81works2.02yr avg
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Research Topics

Immune cells in cancer(32), Glioma Diagnosis and Treatment(26), MicroRNA in disease regulation(12), Neuroinflammation and Neurodegeneration Mechanisms(11), Immunotherapy and Immune Responses(10)

Publications81 total

Adoptive cell therapy with macrophage-drug conjugates facilitates cytotoxic drug transfer and immune activation in glioblastoma models
Science Translational Medicine·2025· 6 cited
Adoptive cell therapy with macrophage-drug conjugates facilitates cytotoxic drug transfer and immune activation in glioblastoma models
Universität Zürich, ZORA·2025Open Access
Abstract 6174: Macrophage-based immunotherapy of platinum-resistant ovarian cancer
Cancer Research·2025
Single-Cell Cloning of Breast Cancer Cells Secreting Specific Subsets of Extracellular Vesicles
Cancers·2021· 27 citedOpen Access
Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells
Journal of Clinical Investigation·2021· 235 citedOpen Access
Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer
2020
Abstract 2193: Small molecule inducible MyD88/CD40 (iMC) in CAR-T cells can repolarize M2 macrophage to an anti-tumor M1 phenotype
Cancer Research·2020
Abstract 2180: Genetically engineered chimeric antigen receptor (CAR) monocytes demonstrate targeted anti-tumor activity and differentiate into M1-polarized CAR macrophages
Cancer Research·2020· 4 cited
Abstract 3242: CT-0508 is an anti-HER2 chimeric antigen receptor (CAR) macrophage with targeted anti-tumor activity that promotes a pro-inflammatory solid tumor microenvironment
Cancer Research·2020· 3 cited
Inhibition of the αv integrin-TGF-β axis improves natural killer cell function against glioblastoma stem cells
2020· 5 cited
Human chimeric antigen receptor macrophages for cancer immunotherapy
Nature Biotechnology·2020· 1.3k citedOpen Access
Abstract B65: CT-0508, a novel CAR macrophage product directed against HER2, promotes a proinflammatory tumor microenvironment
Cancer Immunology Research·2020· 5 cited
Abstract 2907: Exosome secretion is an inheritable property of cancer cells: Single-cell profiling of exosome secretion
Tumor Biology·2019Open Access
Abstract 2907: Exosome secretion is an inheritable property of cancer cells: Single-cell profiling of exosome secretion
Cancer Research·2019
Knockout immune regulator FGL2 in tumor cells impairs tumor progression in the CNS by facilitating CD103+ dendritic cell differentiation
The Journal of Immunology·2019
Author Correction: FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation
Nature Communications·2019· 11 citedOpen Access
FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation
Nature Communications·2019· 116 citedOpen Access
TMIC-26. MiR-181a CONTROLS THE OSTEOPONTIN-MEDIATED IMMUNE CIRCUIT IN GLIOBLASTOMA
Neuro-Oncology·2018Open Access
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target
Journal of Clinical Investigation·2018· 392 citedOpen Access
Cell surface vimentin-targeted monoclonal antibody 86C increases sensitivity to temozolomide in glioma stem cells
Cancer Letters·2018· 36 citedOpen Access
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Frequent Co-authors

Amy B. Heimberger(30), Jun Wei(17), Ling-Yuan Kong(10), Gregory N. Fuller(10), Bożena Kamińska(10), Shouhao Zhou(9), Shulin Li(9), Jun Yan(8), Xueqing Xia(8), Yuuri Hashimoto(7), Joy Gumin(7), Nahir Cortes‐Santiago(7), Erik P. Sulman(6), Edjah K. Nduom(6), George A. Călin(6), Juàn Fueyo(6), Candelaria Gomez‐Manzano(6), Nasser K. Yaghi(5), Neal Huang(5), Xiaoyang Ling(5)