Iosif Pediaditakis

Forma Therapeutics (United States) — United States

Neuroscience · Life Sciences

14h-index884citations19works0.02yr avg
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Research Topics

Nerve injury and regeneration(7), Neurogenesis and neuroplasticity mechanisms(5), Neuropeptides and Animal Physiology(4), Barrier Structure and Function Studies(3), Parkinson's Disease Mechanisms and Treatments(2)

Publications19 total

Pharmacological modulation of the blood-brain barrier: Mechanisms, therapeutic strategies, and emerging technologies
Pharmacological Reviews·2026
A microengineered Brain-Chip to model neuroinflammation in humans
iScience·2022· 79 citedOpen Access
A Microengineered Brain-Chip to Model Neuroinflammation in Humans
2022· 2 citedOpen Access
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption
Nature Communications·2021· 211 citedOpen Access
Modeling Alpha-Synuclein Pathology in a Human Brain-Chip to Assess Blood-Brain Barrier Disruption in Parkinson’s Disease
2020· 9 citedOpen Access
BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the “weaver” mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor
Neuropharmacology·2017· 26 cited
Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer
Scientific Reports·2017· 50 citedOpen Access
Synthetic microneurotrophins in therapeutics of neurodegeneration
Oncotarget·2017· 10 citedOpen Access
BNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis
Frontiers in Pharmacology·2016· 34 citedOpen Access
Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation
Neuropharmacology·2016· 44 cited
Dehydroepiandrosterone: An Ancestral Ligand of Neurotrophin Receptors
Endocrinology·2014· 44 citedOpen Access
Differential Effects of Dehydroepiandrosterone and Testosterone in Prostate and Colon Cancer Cell Apoptosis: The Role of Nerve Growth Factor (NGF) Receptors
Endocrinology·2013· 51 citedOpen Access
Direct laser texturing of biomimetic surfaces for neural tissue engineering
2013
Genetic Dissection of Neurotrophin Signaling through the p75 Neurotrophin Receptor
Cell Reports·2012· 70 citedOpen Access
APRIL Binding to BCMA Activates a JNK2–FOXO3–GADD45 Pathway and Induces a G2/M Cell Growth Arrest in Liver Cells
The Journal of Immunology·2012· 59 citedOpen Access
Pasireotide (SOM230) protects the retina in animal models of ischemia induced retinopathies
Experimental Eye Research·2012· 18 cited
The neurosteroid dehydroepiandrosterone (DHEA) protects the retina from AMPA-induced excitotoxicity: NGF TrkA receptor involvement
Neuropharmacology·2012· 29 cited
ERα17p, an ERα P295-T311 fragment, modifies the migration of breast cancer cells, through actin cytoskeleton rearrangements
Journal of Cellular Biochemistry·2011· 22 cited
Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis
PLoS Biology·2011· 126 citedOpen Access

Frequent Co-authors

Ioannis Charalampopoulos(13), Achille Gravanis(12), Konstantia Kodella(4), Katia Karalis(4), Elias Castanas(4), Dimitris V. Manatakis(3), Chris Hinojosa(3), Ηλίας Σ. Μανωλάκος(3), Lorna Ewart(3), Vasileia Ismini Alexaki(3), Theodora Calogeropoulou(3), George Notas(3), Marilena Kampa(3), Christopher Y. Le(2), Geraldine A. Hamilton(2), Lee L. Rubin(2), Paschalis Efstathopoulos(2), Sonalee Barthakur(2), Alexander G. Sorets(2), Lee E. Rubin(2)