Rena R. Xian

Johns Hopkins University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index852citations107works1.92yr avg
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Research Topics

Cancer Genomics and Diagnostics(53), Lymphoma Diagnosis and Treatment(24), Genetics, Bioinformatics, and Biomedical Research(22), Viral-associated cancers and disorders(19), Health and Medical Research Impacts(18)

Publications107 total

SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
Clinical Cancer Research·2026
Optical Genome Mapping for Cytogenetic Analysis in Multiple Myeloma: Real‐World Evidence
American Journal of Hematology·2026Open Access
EBV INFECTION OUTCOMES DETERMINED BY MONOCYTE AND T <sub>REG</sub> -DRIVEN IMMUNE DYNAMICS IN AN EX VIVO PBMC MODEL
2025Open Access
A multi-site break through cancer pilot study testing the feasibility and safety of therapeutic intervention for patients with high-risk clonal cytopenia of undetermined significance (CCUS)
Blood·2025
Methylation-specific qPCR for the EBV C promoter to quantify EBV methylation
Infectious Agents and Cancer·2025Open Access
C-C motif chemokine receptor-like 2 promotes the interferon-γ signaling response in myeloid neoplasms with erythroid differentiation and mutated &lt;i&gt;TP53&lt;/i&gt;
Haematologica·2025· 2 citedOpen Access
Circulating plasma EBV DNA: a potential tool to facilitate diagnosis of pediatric Burkitt lymphoma in sub-Saharan Africa
Blood Global Hematology·2025· 1 citedOpen Access
Elimination of BRAF p.V600E under selective pressure of BRAF-targeted therapy and expansion of a PIK3CA p.E542K clone in a patient with recurrent malignant glomus tumor
2025Open Access
OnPOINT: Development of an open navigator through precision oncology informatics technology to support precision oncology decisions and genotype-matched clinical trial enrollment.
Journal of Clinical Oncology·2025
Liquid biopsy-informed precision oncology clinical trial to evaluate the utility of ctDNA genomic profiling in patients with advanced or metastatic solid tumors.
Journal of Clinical Oncology·2025
Full-Length Clonal Immunoglobulin Rearrangements in cfDNA: Improved Recovery and Sequencing
Clinical Chemistry·2025
Prolonged Diagnostic Interval Leads to High Lymphoma Related Mortality in a Prospective Cohort of People with HIV Undergoing Fine Needle Aspiration
Cancers·2025· 1 citedOpen Access
1836 Next Generation Sequencing Variant Call Artifacts in Archival FFPE Tissues and Successful Restoration with a DNA Repair Enzyme
Laboratory Investigation·2025Open Access
CCRL2 promotes the interferon-γ signaling response in myeloid neoplasms with erythroid differentiation and mutated <i>TP53</i>
2025· 2 citedOpen Access
Diagnostic and Prognostic/Therapeutic Significance of Comprehensive Analysis of Bone and Soft Tissue Tumors Using Optical Genome Mapping and Next-Generation Sequencing
Modern Pathology·2024· 12 cited
Genomic Reporting Practices Across 5 Molecular Disciplines: A Study From the College of American Pathologists
Archives of Pathology & Laboratory Medicine·2024· 2 citedOpen Access
CCRL2 As a Novel Target in Acute Erythroid Leukemia
Blood·2024
High Molecular Risk Mutations (HMR) Drive Progression of <i>CALR</i>-mutated Myeloproliferative Neoplasm (MPN)
Blood·2024
The Era of Molecular Hematopathology
Journal of Molecular Diagnostics·2024
Poly (ADP-ribose) Polymerase Inhibitor Resistance Driven by Emergence of Polyclonal Mutations With Convergent Evolution: A Molecular Tumor Board Discussion
JCO Precision Oncology·2024· 4 citedOpen Access
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Frequent Co-authors

Christopher D. Gocke(18), Richard F. Ambinder(10), James R. Eshleman(10), Aparna Pallavajjala(6), Lisa Haley(5), Ming‐Tseh Lin(5), Ming-Tseh Lin(5), Valsamo Anagnostou(5), Jessica J. Tao(5), Neil Martinson(5), Erika F. Rodriguez(4), Li‐Hui Tseng(4), Ying Zou(4), Samantha L. Vogt(4), Tanvier Omar(4), Mark J. Levis(4), Jordan Cheng(3), David Chia(3), Charles M. Strom(3), Michael Tu(3)