Costas D. Maranas

Pennsylvania State University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

82h-index21.5kcitations371works9.12yr avg
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Research Topics

Microbial Metabolic Engineering and Bioproduction(199), Biofuel production and bioconversion(97), Gene Regulatory Network Analysis(63), Enzyme Catalysis and Immobilization(61), Process Optimization and Integration(28)

Publications371 total

High yield production of 3-hydroxypropionic acid using Issatchenkia orientalis
Nature Communications·2026· 2 citedOpen Access
Building an expanded bio-based economy through synthetic biology
Biotechnology Advances·2025· 1 cited
Metabolic flux and resource balance in the oleaginous yeast Rhodotorula toruloides
Metabolic Engineering·2025
Parameterization of cell-free systems with time-series data using KETCHUP
PLoS Computational Biology·2025Open Access
BindPred: A Framework for Predicting Protein-Protein Binding Affinity from Language Model Embeddings
2025Open Access
MechFind: A computational framework for de novo prediction of enzyme mechanisms
2025Open Access
Reconstruction of a resource balance analysis model of Clostridium thermocellum examines the metabolic cost of glycolytic and cellulosome enzymes
Metabolic Engineering·2025
novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection
PLoS Computational Biology·2025Open Access
Parameterization of cell-free systems with time-series data using KETCHUP
2025
Reframing the role of the objective function in its proper context for metabolic network modeling
Cell Systems·2025· 4 cited
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid
ACS Synthetic Biology·2025· 1 cited
CatPred: a comprehensive framework for deep learning in vitro enzyme kinetic parameters
Nature Communications·2025· 52 citedOpen Access
minChemBio: Expanding Chemical Synthesis with Chemo-Enzymatic Pathways Using Minimal Transitions
ACS Synthetic Biology·2025· 1 citedOpen Access
novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection
2024· 3 citedOpen Access
FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models
2024· 7 citedOpen Access
Current State, Challenges, and Opportunities in Genome-Scale Resource Allocation Models: A Mathematical Perspective
Metabolites·2024· 13 citedOpen Access
CatPred: A comprehensive framework for deep learning in vitro enzyme kinetic parameters kcat, Km and Ki
2024· 2 citedOpen Access
Dehydrated Biomimetic Membranes with Skinlike Structure and Function
ACS Applied Materials & Interfaces·2024· 8 cited
CatPred: A comprehensive framework for deep learning in vitro enzyme kinetic parameters <i> k <sub>cat</sub> </i> , <i> K <sub>m</sub> </i> and <i> K <sub>i</sub> </i>
2024· 3 citedOpen Access
Mitochondrial ATP generation is more proteome efficient than glycolysis
Nature Chemical Biology·2024· 95 citedOpen Access
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Frequent Co-authors

Anthony P. Burgard(7), Christodoulos A. Floudas(6), Patrick F. Suthers(6), Chiam Yu Ng(5), Ali R. Zomorrodi(5), Siu Hung Joshua Chan(4), Priti Pharkya(4), Lin Wang(3), Anshuman Gupta(3), Sridhar Ranganathan(3), Vinay Kumar(3), Andrew D. Patterson(3), Bernhard Ø. Palsson(2), Ioannis P. Androulakis(2), Madhukar S. Dasika(2), Rajib Saha(2), Himadri B. Pakrasi(2), Ali Khodayari(2), Margaret Simons(2), Howard M. Salis(2)