Simon H. Reed

Cardiff University — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index1.9kcitations85works1.42yr avg
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Research Topics

DNA Repair Mechanisms(52), Genomics and Chromatin Dynamics(32), CRISPR and Genetic Engineering(27), RNA modifications and cancer(9), DNA and Nucleic Acid Chemistry(8)

Publications85 total

The CML and the ALL inducing isoforms of BCR::ABL1 differ for the induction of genomic instablity
Blood·2025Open Access
Association of DDR pathway proteins and breast cancer risk in a Pakistani population
Future Oncology·2025Open Access
INDUCE-seq®: Ensuring the safe development of cell and gene therapies by gene editing
Cytotherapy·2025
Inducible estrogen receptor alpha in normal breast epithelial cells demonstrate estrogen receptor-dependent DNA damage
2025Open Access
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability
2024Open Access
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication
Nature Communications·2024· 2 citedOpen Access
Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article
Human Gene Therapy·2024· 6 citedOpen Access
INDUCE-seq: ENSURING THE SAFE DEVELOPMENT OF CELL AND GENE THERAPIES BY GENE EDITING
Cytotherapy·2024
Long non-coding RNA LIP interacts with PARP-1 influencing the efficiency of base excision repair
Non-coding RNA Research·2024· 7 citedOpen Access
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication
2024Open Access
Long Non-Coding Rna Lip Interacts with Parp-1 Influencing the Efficiency of Base Excision Repair
SSRN Electronic Journal·2024Open Access
Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Molecular Cell·2023· 40 citedOpen Access
Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology
Mutagenesis·2023· 6 citedOpen Access
DNA replication initiation shapes the mutational landscape and expression of the human genome
Science Advances·2022· 33 citedOpen Access
To incise or not and where: SET-domain methyltransferases know
Trends in Biochemical Sciences·2022· 10 citedOpen Access
Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq
Nature Communications·2022· 35 citedOpen Access
A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer
Molecular Cancer·2022· 34 citedOpen Access
A novel MiR-346-Directed DNA damage mechanism is regulated by its interaction with long non-coding RNA, NORAD, in prostate cancer
Endocrine Abstracts·2021
Carcinogen-induced DNA structural distortion differences in the RAS gene isoforms; the importance of local sequence
BMC Chemistry·2021· 10 citedOpen Access
Abstract 2362: Long non-coding RNA NORAD interaction with miR-346 impacts DNA damage response and anti-tumor immunity in prostate cancer
Cancer Research·2021· 1 cited
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Frequent Co-authors

Raymond Waters(22), Shirong Yu(12), Yumin Teng(11), Errol C. Friedberg(8), Patrick van Eijk(8), Yachuan Yu(5), Zheng Zhou(5), Mark K. Bennett(5), Katie Evans(5), Wenya Huang(4), Stephen Albert Johnston(3), Thomas G. Gillette(3), William J. Feaver(3), Richard Webster(3), Steven Jon Russell(2), Hairong Liu(2), Zhigang Wang(2), Shuguang Wei(2), Bruce Stillman(2), Tom Owen‐Hughes(2)