Valentina Cecchinato

Università della Svizzera italiana — Switzerland

Medicine · Health Sciences

25h-index1.9kcitations46works3.22yr avg
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Research Topics

Chemokine receptors and signaling(12), HIV Research and Treatment(11), T-cell and B-cell Immunology(9), Immunotherapy and Immune Responses(9), Immune Cell Function and Interaction(9)

Publications46 total

A Potent Nonapeptide Inhibitor for the CXCL12/HMGB1 heterocomplex: A Computational and Experimental Approach
2025Open Access
A potent nonapeptide inhibitor for the CXCL12/HMGB1 heterocomplex: A computational and experimental approach
Computational and Structural Biotechnology Journal·2025· 1 citedOpen Access
Function of Chemokines and Their Receptors in Immunity
Elsevier eBooks·2024
Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration
Frontiers in Immunology·2024· 10 citedOpen Access
Patients with ankylosing spondylitis present a distinct CD8 T cell subset with osteogenic and cytotoxic potential
RMD Open·2024· 5 citedOpen Access
The chemokine landscape: one system multiple shades
Frontiers in Immunology·2023· 26 citedOpen Access
Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
Nature Immunology·2023· 89 citedOpen Access
Anti-chemokine antibodies after SARS-CoV-2 infection correlate with favorable disease course
2022· 7 citedOpen Access
Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction
Journal of Medicinal Chemistry·2021· 20 citedOpen Access
β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4
Frontiers in Immunology·2020· 35 citedOpen Access
Systematic development of peptide inhibitors targeting the CXCL12/HMGB1 interaction
2019· 3 citedOpen Access
Oxidation state dependent conformational changes of HMGB1 regulates the formation of the CXCL12/HMGB1 heterocomplex
2019Open Access
Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
Computational and Structural Biotechnology Journal·2019· 27 citedOpen Access
Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity
Frontiers in Immunology·2018· 37 citedOpen Access
Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis
Frontiers in Immunology·2018· 52 citedOpen Access
Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration
British Journal of Anaesthesia·2018· 77 citedOpen Access
Insight on the regulation of chemokine activities
Journal of Leukocyte Biology·2018· 9 citedOpen Access
Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination
Frontiers in Immunology·2017· 23 citedOpen Access
Epithelial chemokine CXCL14 synergizes with CXCL12 <i>via</i> allosteric modulation of CXCR4
The FASEB Journal·2017· 67 citedOpen Access
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
The Journal of Immunology·2016· 24 citedOpen Access
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Frequent Co-authors

Mariagrazia Uguccioni(23), Genoveffa Franchini(18), Gianluca D’Agostino(10), Monica Vaccari(9), Vibeke Andresen(8), Andrea Cavalli(8), Jacopo Sgrignani(8), Robyn Washington Parks(7), Marcus Thelen(7), Gabriela Danelon(7), Jean‐Michel Héraud(6), David Venzon(6), Adriano Boasso(6), Enrico Mario Alessandro Fassi(6), Giovanni Grazioso(6), Raffaella Chiaramonte(5), Risaku Fukumoto(5), Christophe Nicot(5), Elżbieta Tryniszewska(4), Andrea Basile(4)