Huw M. L. Davies

Emory University — United States

Chemistry · Physical Sciences

96h-index33.9kcitations847works5.72yr avg
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Research Topics

Cyclopropane Reaction Mechanisms(500), Catalytic C–H Functionalization Methods(351), Synthesis and Catalytic Reactions(143), Asymmetric Synthesis and Catalysis(131), Crystallization and Solubility Studies(127)

Publications845 total

Data-driven copper catalysis enables stereoselective fluorocyclopropanation
Chem·2026
Asymmetric C–H Functionalization of Bicyclo[2.1.1]hexanes and Their 2-Oxa- and 2-Aza Derivatives via Rhodium Carbene Intermediates
Journal of the American Chemical Society·2026Open Access
A novel drug series optimized to address cystic fibrosis and other CFTR deficiency diseases of human airways
npj Drug Discovery.·2025Open Access
Academic–Industrial Collaboration in Synthesis with Real-Time Impact in Medicinal Chemistry: Discovery of Cystic Fibrosis C2 Corrector ABBV-602
ACS Medicinal Chemistry Letters·2025Open Access
Enantioselective and Diastereoselective Synthesis of Azaspiro[n.2]alkanes by Rhodium-Catalyzed Cyclopropanations
ACS Catalysis·2025· 2 citedOpen Access
Direct Synthesis of Bicyclo[1.1.1]pentanes by Sequential C═C, C–C Functionalization Reactions
Journal of the American Chemical Society·2025· 11 citedOpen Access
Asymmetric C–H Functionalization of <i>N</i>-Boc-2,5-dihydro-1<i>H</i>-pyrrole and Its Application as a Key Step in the Synthesis of (−)-Dragocin D
Journal of the American Chemical Society·2025· 2 citedOpen Access
Impact of Induced Fitting and Secondary Noncovalent Interactions on Site-Selective and Enantioselective C–H Functionalization of Arylcyclohexanes
Journal of the American Chemical Society·2025· 4 citedOpen Access
Enantioselective and Diastereoselective Synthesis of Spiroazabicyclo[2.n]alkanes by Rhodium-Catalyzed Cyclopropanations
2025· 1 citedOpen Access
Direct Synthesis of 2-Substitued Bicyclo[1.1.1]pentanes by Sequential C=C, C–C Functionalization Reactions
2025· 4 citedOpen Access
Hexafluoroisopropanol Solvent Effects on Enantioselectivity of Dirhodium Tetracarboxylate-Catalyzed Cyclopropanation
Journal of the American Chemical Society·2025· 5 citedOpen Access
<i>C</i><sub>4</sub>-Symmetric Bowl-Shaped Diruthenium Tetracarboxylate Catalysts for Enantioselective C–H Functionalization Using Donor/Acceptor Carbenes
ACS Catalysis·2025· 2 citedOpen Access
Diversity Synthesis Using Glutarimides as Rhodium Carbene Precursors in Enantioselective C–H Functionalization and Cyclopropanation
Journal of the American Chemical Society·2025· 6 citedOpen Access
HFIP Solvent Effects on Enantioselectivity of Dirhodium Tetracar-boxylate-Catalyzed Cyclopropanation
2025Open Access
Stereoselective Synthesis of Highly Functionalized Bicyclo[2.1.0]pentanes by Sequential [2 + 1] and [2 + 2] Cycloadditions
Organic Letters·2025· 10 citedOpen Access
Molecular Dynamics of the Davies Ambimodal C–H Functionalization/Cope Rearrangement Reaction
The Journal of Organic Chemistry·2024· 6 citedOpen Access
Total synthesis of (−)-cylindrocyclophane A facilitated by C−H functionalization
Science·2024· 19 citedOpen Access
Facile Recovery and Recycling of a Soluble Dirhodium Catalyst in Asymmetric Cyclopropanation via a Catalyst-in-Bag System
Organic Process Research & Development·2024· 2 citedOpen Access
Correction to “Leveraging Regio- and Stereoselective C(sp<sup>3</sup>)–H Functionalization of Silyl Ethers to Train a Logistic Regression Classification Model for Predicting Site-Selectivity Bias”
Journal of the American Chemical Society·2024
Asymmetric Dirhodium-Catalyzed Modification of Immunomodulatory Imide Drugs and Their Biological Assessment
ACS Medicinal Chemistry Letters·2024· 5 citedOpen Access
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Frequent Co-authors

Djamaladdin G. Musaev(5), Daniel Morton(4), Kuangbiao Liao(4), Vyacheslav Boyarskikh(4), Jørn H. Hansen(4), Tore Hansen(3), Yajing Lian(3), Ravisekhara P. Reddy(3), Jochen Autschbach(3), James R. Manning(2), Joshua S. Alford(2), Jin‐Quan Yu(2), Justin R. Denton(2), John Bacsa(2), Jillian E. Spangler(2), Melvyn Rowen Churchill(2), Matthew S. Long(2), John F. Briones(2), Changming Qin(2), Rohan E. J. Beckwith(1)