Lukasz J. Ochyl

Xencor (United States) — United States

Immunology and Microbiology · Life Sciences

17h-index3.3kcitations29works0.02yr avg
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Research Topics

Immunotherapy and Immune Responses(18), Cancer Immunotherapy and Biomarkers(6), RNA Interference and Gene Delivery(6), Immune Response and Inflammation(4), Nanoplatforms for cancer theranostics(4)

Publications28 total

1079 LAG3-targeted IL15/IL15Rα-Fc (LAG3 x IL15) fusion proteins for preferential TIL expansion via cis delivery of IL15 to LAG3+ cells
Regular and Young Investigator Award Abstracts·2022Open Access
Abstract 2080: LAG3-targeted IL15/IL15Rα-Fc (LAG3 x IL15) fusion proteins for preferential TIL expansion
Cancer Research·2022· 4 cited
872 PD1 x TGFbR2 and CD5 x TGFbR2 bispecifics selectively block TGFbR2 on target-positive T cells, promote T cell activation, and elicit an anti-tumor response in solid tumors
Regular and Young Investigator Award Abstracts·2021Open Access
Lipid-based vaccine nanoparticles for induction of humoral immune responses against HIV-1 and SARS-CoV-2
Journal of Controlled Release·2020· 46 citedOpen Access
714 PD1 x TGFβR2 bispecifics selectively block TGFβR2 on PD1-positive T cells, promote T cell activation, and elicit an anti-tumor response in solid tumors
Regular and Young Investigator Award Abstracts·2020Open Access
Engineered Ovalbumin Nanoparticles for Cancer Immunotherapy
Advanced Therapeutics·2020· 45 citedOpen Access
Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination
Nano Letters·2020· 89 citedOpen Access
Extracellular Trap‐Mimicking DNA‐Histone Mesostructures Synergistically Activate Dendritic Cells
Advanced Healthcare Materials·2019· 9 citedOpen Access
Dendritic Cell Membrane Vesicles for Activation and Maintenance of Antigen‐Specific T Cells
Advanced Healthcare Materials·2018· 46 citedOpen Access
Vaccine nanoparticles displaying recombinant Ebola virus glycoprotein for induction of potent antibody and polyfunctional T cell responses
Nanomedicine Nanotechnology Biology and Medicine·2018· 24 citedOpen Access
Interrogation of Antigen Display on Individual Vaccine Nanoparticles for Achieving Neutralizing Antibody Responses against Hepatitis C Virus
Nano Letters·2018· 30 citedOpen Access
Self‐healing encapsulation and controlled release of vaccine antigens from PLGA microparticles delivered by microneedle patches
Bioengineering & Translational Medicine·2018· 59 citedOpen Access
PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy
Biomaterials·2018· 114 citedOpen Access
Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy
Journal of Controlled Release·2018· 132 cited
Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer
Nature Communications·2018· 791 citedOpen Access
Preparation and Characterization of Cell Membranes for Cancer Immunotherapy
Deep Blue (University of Michigan)·2018Open Access
Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy
DSpace@MIT (Massachusetts Institute of Technology)·2017Open Access
Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy
Nano Letters·2017· 216 citedOpen Access
Self-encapsulating Poly(lactic-<i>co</i>-glycolic acid) (PLGA) Microspheres for Intranasal Vaccine Delivery
Molecular Pharmaceutics·2017· 39 citedOpen Access
Toward a Single‐Dose Vaccination Strategy with Self‐Encapsulating PLGA Microspheres
Advanced Healthcare Materials·2017· 42 citedOpen Access
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Frequent Co-authors

James J. Moon(20), Rui Kuai(7), Yao Xu(6), Anna Schwendeman(4), Joseph Bazzill(4), Suzanne Schubbert(4), Christine Bonzon(4), Rumana Rashid(4), Kendra N. Avery(4), John R. Desjarlais(4), Jutaek Nam(3), Sejin Son(3), Yuchen Fan(3), Steven P. Schwendeman(3), Preety Sahdev(2), Darrell J. Irvine(2), Alireza Hassani Najafabadi(2), Lindsay Scheetz(2), James J. Moon(2), Brittany A. Bailey(2)