Beatrice Alexander-Howden

Wellcome Centre for Cell Biology — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

4h-index109citations11works0.02yr avg
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Research Topics

Genetics and Neurodevelopmental Disorders(6), Renal and related cancers(4), Cancer-related gene regulation(3), Autism Spectrum Disorder Research(2), Pluripotent Stem Cells Research(2)

Publications11 total

Pervasive binding of the stem cell transcription factor SALL4 shapes the chromatin landscape
2025
Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach
2025Open Access
MeCP2 requires interactions with nucleosome linker DNA to read chromatin DNA methylation
2025Open Access
Dysfunction of a SET3-like complex underlies a family of related neurological disorders
2025Open Access
A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay
Scientific Reports·2023· 2 citedOpen Access
Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome
Life Science Alliance·2023· 16 citedOpen Access
Structural analysis of SALL4 zinc-finger domain reveals a link between AT-rich DNA binding and Okihiro syndrome
2022Open Access
SALL4 controls cell fate in response to DNA base composition
Molecular Cell·2021· 51 citedOpen Access
SALL4 controls cell fate in response to DNA base composition
2020· 4 citedOpen Access
A mutation-led search for novel functional domains in MeCP2
Human Molecular Genetics·2018· 36 citedOpen Access
A mutation-led search for novel functional domains in MeCP2
2018Open Access

Frequent Co-authors

Adrian Bird(11), Kashyap Chhatbar(6), Raphaël Pantier(5), Jim Selfridge(5), Jacky Guy(5), Atlanta G. Cook(4), Timo Quante(3), James A. Watson(3), Tricia Mathieson(3), Konstantina Skourti-Stathaki(2), Justyna Cholewa-Waclaw(2), Grace Alston(2), Heng Yang Lee(2), Cornelia G. Spruijt(2), Michiel Vermeulen(2), Laura FitzPatrick(2), Dina DeSousa(2), Martha V. Koerner(2), Uma Jayachandran(2), Valdeko Kruusvee(2)