Oscar G. Wilkins

Queen Mary University of London — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index1.3kcitations27works22.82yr avg
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Research Topics

RNA Research and Splicing(14), Amyotrophic Lateral Sclerosis Research(12), RNA and protein synthesis mechanisms(11), RNA modifications and cancer(6), Neurogenetic and Muscular Disorders Research(6)

Publications26 total

Collective homeostasis of condensation-prone proteins via their mRNAs
Nature·2025· 5 citedOpen Access
Characterisation of LAMP1- and LAMP2A-positive organelles in neurons
2025· 1 citedOpen Access
Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures
Neuron·2025· 19 citedOpen Access
Creation of de novo cryptic splicing for ALS and FTD precision medicine
Science·2024· 27 citedOpen Access
From computational models of the splicing code to regulatory mechanisms and therapeutic implications
Nature Reviews Genetics·2024· 23 cited
Loss of TDP-43 induces synaptic dysfunction that is rescued by UNC13A splice-switching ASOs
2024· 25 citedOpen Access
Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Nature·2024· 3 citedOpen Access
Riboseq-flow: A streamlined, reliable pipeline for ribosome profiling data analysis and quality control
Wellcome Open Research·2024· 2 citedOpen Access
Designing Transgene Vectors for ALS Therapeutics (P11-4.010)
Neurology·2024
Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD
Science Translational Medicine·2024· 134 citedOpen Access
TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD
2024· 23 citedOpen Access
Creation of de novo cryptic splicing for ALS/FTD precision medicine
2023· 5 citedOpen Access
Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale
2023· 3 citedOpen Access
Mutual homeostasis of charged proteins
2023· 6 citedOpen Access
Mis-spliced transcripts generate <i>de novo</i> proteins in TDP-43-related ALS/FTD
2023· 37 citedOpen Access
Identifying ribosome heterogeneity using ribosome profiling
Nucleic Acids Research·2022· 24 citedOpen Access
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Nature·2022· 474 citedOpen Access
An improved iCLIP protocol
2021· 32 citedOpen Access
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation
Science Advances·2021· 63 citedOpen Access
Ribocutter: Cas9-mediated rRNA depletion from multiplexed Ribo-seq libraries
2021· 13 citedOpen Access
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Frequent Co-authors

Jernej Ule(20), Pietro Fratta(11), Matthew J. Keuss(10), Matteo Zanovello(9), Giampietro Schiavo(8), Elizabeth Fisher(8), Sarah E. Hill(7), Yue Qi(7), Towfique Raj(7), Maria Secrier(7), Jack Humphrey(7), Michael E. Ward(7), Flora Lee(6), Hemali Phatnani(6), Anna‐Leigh Brown(6), Martina Hallegger(5), Puja R. Mehta(5), Pietro Fratta(5), Alexander Bampton(4), Laura Masino(4)