Dong Deng

Sichuan University — China

Medicine · Health Sciences

20h-index3.2kcitations69works6.42yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(6), Adenosine and Purinergic Signaling(6), Metabolism, Diabetes, and Cancer(5), Reproductive Biology and Fertility(4), Lipid Membrane Structure and Behavior(4)

Publications69 total

Structural-guided identification of two modulators of β−1,3-glucan synthase FKS1
Nature Communications·2025Open Access
Structural assembly of the subcortical maternal complex SCMC
Structure·2025
NLRP14 modulates the activity of E3 ubiquitin ligases during the oocyte-to-embryo transition
2025Open Access
The subcortical maternal complex safeguards mouse oocyte-to-embryo transition by preventing nuclear entry of SPIN1
Nature Structural & Molecular Biology·2025· 6 cited
Cryo-EM structure of the β-1,3-glucan synthase FKS1-Rho1 complex
Nature Communications·2025· 14 citedOpen Access
Mechanistic insights into proton-coupled substrate translocation of nucleoside proton symporters
Journal of Biological Chemistry·2025Open Access
Substrate and inhibitor specificity of Plasmodium nucleoside transporters ENT1 orthologs
Journal of Biological Chemistry·2024Open Access
Structural insights into the inhibition mechanism of fungal GWT1 by manogepix
Nature Communications·2024· 17 citedOpen Access
The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3
Nature Communications·2024· 11 citedOpen Access
Cryo-EM structure of the human subcortical maternal complex and the associated discovery of infertility-associated variants
Nature Structural & Molecular Biology·2024· 11 cited
CEP112 coordinates translational regulation of essential fertility genes during spermiogenesis through phase separation in humans and mice
Nature Communications·2024· 19 citedOpen Access
Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA
Cell Research·2024· 5 citedOpen Access
GPU-based butterfly counting
The VLDB Journal·2024· 1 cited
Homozygous variant in DRC3 (LRRC48) gene causes asthenozoospermia and male infertility
Journal of Human Genetics·2024· 8 cited
Metabolic profiling identifies Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse sperm
Cellular and Molecular Life Sciences·2024· 6 citedOpen Access
Direct and Continuous Monitoring of Multicomponent Antibiotic Gentamicin in Blood at Single-Molecule Resolution
ACS Nano·2024· 11 cited
Mechanism of activation of β-1,3-glucan synthase by Rho1
2024· 1 citedOpen Access
Neural Locality Sensitive Hashing for Entity Blocking
arXiv (Cornell University)·2024· 1 citedOpen Access
Direct single-molecule detection of CoA-SH and ATP by the membrane proteins TMEM120A and TMEM120B
Nanoscale·2024· 2 cited
Structural basis of the subcortical maternal complex and its implications in reproductive disorders
Nature Structural & Molecular Biology·2024· 20 cited
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Frequent Co-authors

Qingjie Xiao(13), Jialu Li(12), Chuangye Yan(11), Nieng Yan(11), Jianping Wu(8), Jia Geng(8), Li Guo(7), Pengliang Chi(7), Xiang Wang(7), Ke Meng(6), Changjian Zhao(6), Yanxia Zhou(6), Luqiu Mou(5), Bo Sun(5), Weidan Yuan(5), Chen Wang(5), Xiaojing Pan(4), Qingting Liu(4), Ruobing Ren(4), Li Guo(4)