Jesper Wengel

University of Southern Denmark — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

62h-index20.2kcitations586works1.72yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(370), Advanced biosensing and bioanalysis techniques(328), RNA Interference and Gene Delivery(183), RNA and protein synthesis mechanisms(95), Carbohydrate Chemistry and Synthesis(56)

Publications586 total

Improved wound healing by dual inhibition of miR-146a-5p and miR-29a-3p supports a network action of dysregulated miRNAs in diabetic skin
Diabetologia·2025· 1 citedOpen Access
Anti-gene oligonucleotides targeting Friedreich’s ataxia expanded GAA⋅TTC repeats increase Frataxin expression
Molecular Therapy — Nucleic Acids·2025· 1 citedOpen Access
Lock, Protect, and Bind: In Vitro Selection of LNA-modified Aptamers Using a Mutant T7 RNA Polymerase
2025Open Access
Author response for "Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in <i>BTK</i>/<i>Tec</i> double deficient X-linked agammaglobulinemia model"
2025
Author response for "Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in <i>BTK</i>/<i>Tec</i> double deficient X-linked agammaglobulinemia model"
2025
Engineered PepFect14 analog for efficient cellular delivery of oligonucleotides
Biomedicine & Pharmacotherapy·2025· 5 citedOpen Access
Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in <i>BTK</i> / <i>Tec</i> double deficient X-linked agammaglobulinemia model
RSC Chemical Biology·2025· 1 citedOpen Access
Anti-gene oligonucleotide clamps invade dsDNA and downregulate huntingtin expression
Molecular Therapy — Nucleic Acids·2024· 6 citedOpen Access
Anti-gene oligonucleotides targeting Friedreich’s ataxia expanded GAA•TTC repeats increase Frataxin expression
2024Open Access
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation
Bioconjugate Chemistry·2024· 3 citedOpen Access
AptaBERT: Predicting aptamer binding interactions
2023· 5 citedOpen Access
Chemical Modifications and Design Influence the Potency of <i>Huntingtin</i> Anti-Gene Oligonucleotides
Nucleic Acid Therapeutics·2023· 7 citedOpen Access
Spectral imaging and nucleic acid mimics fluorescence in situ hybridization (SI-NAM-FISH) for multiplex detection of clinical pathogens
Frontiers in Microbiology·2022· 14 citedOpen Access
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers
Molecular Therapy — Nucleic Acids·2022· 6 citedOpen Access
Evaluation of Gene Expression Knock‐Down by Chemically and Structurally Modified Gapmer Antisense Oligonucleotides
ChemBioChem·2022· 3 citedOpen Access
Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly
Bioconjugate Chemistry·2022· 9 cited
Chirality transmission in macromolecular domains
Nature Communications·2022· 25 citedOpen Access
Polyamine–Oligonucleotide Conjugates: 2′-OMe-Triazole-Linked 1,4,7,10-Tetraazacyclododecane and Intercalating Dyes and Their Effect on the Thermal Stability of DNA Duplexes
Pharmaceutics·2021· 3 citedOpen Access
Exploration of anti EFG1 locked nucleic acid gapmers to control Candida albicans filamentation
Access Microbiology·2021Open Access
Intramuscular Evaluation of Chimeric Locked Nucleic Acid/2′OMethyl-Modified Antisense Oligonucleotides for Targeted Exon 23 Skipping in Mdx Mice
Pharmaceuticals·2021· 2 citedOpen Access
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Frequent Co-authors

Sanjay K. Singh(10), Vivek K. Rajwanshi(9), Alexei A. Koshkin(7), Ravindra Kumar(7), Mads D. Sørensen(7), Birte Vester(6), Michael Petersen(6), Jørgen Kjems(6), Poul Nielsen(5), Jesper B. Bramsen(5), B. Ravindra Babu(5), Jens Peter Jacobsen(5), Michael Meldgaard(4), Carl Erik Olsen(4), Piet Herdewijn(4), Rakesh N. Veedu(4), Maria Bach Laursen(3), Niels Langkjær(3), Kent Bondensgaard(3), Katrine E. Nielsen(3)