Jun Nakae

International University of Health and Welfare — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

45h-index11.0kcitations127works2.02yr avg
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Research Topics

FOXO transcription factor regulation(37), Pancreatic function and diabetes(26), Metabolism, Diabetes, and Cancer(23), Adipose Tissue and Metabolism(20), Sexual Differentiation and Disorders(17)

Publications127 total

Macrophages play a crucial role in vascular smooth muscle cell coverage
Development·2024· 2 citedOpen Access
FOXO1 represses lymphatic valve formation and maintenance via PRDM1
Cell Reports·2021· 20 citedOpen Access
Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes
Communications Biology·2020· 32 citedOpen Access
The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase–leukotriene B <sub>4</sub> axis
Proceedings of the National Academy of Sciences·2020· 38 citedOpen Access
Tissue-Specific Metabolic Regulation of FOXO-Binding Protein: FOXO Does Not Act Alone
Cells·2020· 57 citedOpen Access
FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression
iScience·2019· 11 citedOpen Access
Foxo in T Cells Regulates Thermogenic Program through Ccr4/Ccl22 Axis
iScience·2019· 5 citedOpen Access
Islet β-cell-produced NUCB2/nesfatin-1 maintains insulin secretion and glycemia along with suppressing UCP-2 in β-cells
The Journal of Physiological Sciences·2019· 23 citedOpen Access
2184-P: Foxo1-CoF Repressor (FCoR) Regulates Pancreatic Alpha- and Beta-Cell Identity by both DNA and Histone Methylation
Diabetes·2019
Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1
iScience·2019· 16 citedOpen Access
Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation
Scientific Reports·2018· 23 citedOpen Access
Foxo1 Corepressor (FCoR) and Foxo1 Regulate a-Cell and ß-Cell Identity
Diabetes·2018
Protective role of AgRP neuron's PDK1 against salt-induced hypertension
Biochemical and Biophysical Research Communications·2018· 7 cited
PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis
Molecular Metabolism·2017· 19 citedOpen Access
Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-dependent Manner
The Molecular Biology Society of Japan·2016
Foxo1 CoRepressor (FCoR) and Foxo1 control α-cell and β-cell identity through regulation of Arx expression
The Molecular Biology Society of Japan·2016
Foxo in T cells inhibits the thermogenic program of brown and subcutaneous adipose tissue.
The Molecular Biology Society of Japan·2016
Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner
Cell Metabolism·2016· 190 citedOpen Access
Involvement of SIK3 in Glucose and Lipid Homeostasis in Mice
PLoS ONE·2012· 76 citedOpen Access
Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance
Diabetes·2012· 60 citedOpen Access
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Frequent Co-authors

Domenico Accili(24), Tadahiro Kitamura(15), Toshihiro Tajima(11), Kenji Fujieda(11), Yoshiaki Kido(8), Yukari Kitamura(5), Masato Kasuga(5), Nozomi Shinohara(5), William Biggs(4), Karen C. Arden(4), Morris F. White(4), Yongheng Cao(4), Yoshitake Hayashi(4), Argiris Efstratiadis(4), Christopher V.E. Wright(3), Masafumi Onodera(3), Hiroshi Itoh(3), Miyo Oki(3), Kristy Iskandar(3), Shouhong Xuan(3)