Jens Fielitz

Max Delbrück Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

37h-index5.4kcitations114works0.92yr avg
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Research Topics

Muscle Physiology and Disorders(25), Signaling Pathways in Disease(13), Mitochondrial Function and Pathology(11), Intensive Care Unit Cognitive Disorders(11), Cardiac Fibrosis and Remodeling(11)

Publications113 total

Abstract 4340599: The Novel Muscle-specific RING Finger-2 Target Sorting Nexin 5 Regulates Protein kinase A Activity through Stabilization of Protein Kinase A Regulatory Subunit Type Iα and Controls Myogenic Differentiation
Circulation·2025
Abstract 4346138: Cardiomyocyte-Specific TFEB Deletion Induces Age-Dependent Heart Failure, Exacerbated by Starvation
Circulation·2025
Hyperactivity of the non-canonical inflammasome in SPG11 and SPG48
EBioMedicine·2025Open Access
The Novel MuRF2 Target SNX5 Regulates PKA Activity Through Stabilization of RI‐α and Controls Myogenic Differentiation
Journal of Cachexia Sarcopenia and Muscle·2025Open Access
Identification of novel human cellular substrates of <i>Staphylococcus aureus</i> serine protease SplB
2025Open Access
Early regulation and alternative splicing dynamics in glucocorticoid muscle atrophy revealed by temporal omics in C2C12 myotubes
American Journal of Physiology-Cell Physiology·2025Open Access
Pro-inflammatory cytokines as regulators of protein tyrosine phosphatases and insulin signaling in murine skeletal muscle cells
Cellular Signalling·2025· 3 citedOpen Access
Integrated Multi-omic Profiling Reveals Early Regulatory Events in Dexamethasone Muscle Atrophy
2025
Circadian Clock Genes Are Differentially Expressed in Skeletal Muscle of Mice With Sepsis – Induced Muscle Atrophy
American Journal of Respiratory and Critical Care Medicine·2025
Distinct diurnal temperature rhythm patterns in critical illness myopathy: secondary analysis of two prospective trials
Annals of Intensive Care·2025Open Access
Muscle RING-finger proteins (MuRF) regulate protein kinase A activity via retrograde vesicular transport of PKA RI-alpha
European Heart Journal·2024Open Access
Skeletal myocyte-specific knockout of Ptpn1 and Ptpn2 enhances inflammatory response in muscle and increases mortality in polymicrobial sepsis
European Heart Journal·2024
Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins
International Journal of Molecular Sciences·2024· 3 citedOpen Access
Increased Expression of Proinflammatory Genes in Peripheral Blood Cells Is Associated with Cardiac Cachexia in Patients with Heart Failure with Reduced Ejection Fraction
Journal of Clinical Medicine·2024· 3 citedOpen Access
Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice
Frontiers in Cardiovascular Medicine·2024· 5 citedOpen Access
Mammalian target of rapamycin inhibition impacts energy homeostasis and induces sex‐specific body weight loss in humans
Journal of Cachexia Sarcopenia and Muscle·2023· 6 citedOpen Access
Abstract P2039: Alteration In Intercalated Disc Composition Impacts Cardiac Disease Progression
Circulation Research·2023
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function
Acta Pharmacologica Sinica·2023· 48 citedOpen Access
Longitudinal Clinical Features of Post-COVID-19 Patients—Symptoms, Fatigue and Physical Function at 3- and 6-Month Follow-Up
Journal of Clinical Medicine·2023· 29 citedOpen Access
SPSB1‐mediated inhibition of TGF‐β receptor‐II impairs myogenesis in inflammation
Journal of Cachexia Sarcopenia and Muscle·2023· 14 citedOpen Access
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Frequent Co-authors

Eric N. Olson(11), Melanie Kny(10), Steffen Weber‐Carstens(10), Vera Regitz‐Zagrosek(10), Tobias Wollersheim(7), Rhonda Bassel‐Duby(6), Sibylle Schmidt(6), Friedrich C. Luft(6), Claudia Spies(6), Simone Spuler(6), James A. Richardson(5), John M. Shelton(5), Christian Kleber(5), Joachim Spranger(5), Reinhard Pregla(5), Roland Hetzer(5), Franziska Schmidt(5), Alexander Hahn(4), Stephan B. Felix(4), Jida Hamati(4)