Sylvia van Drunen Littel‐van den Hurk

University of Saskatchewan — Canada

Medicine · Health Sciences

47h-index7.1kcitations197works13.02yr avg
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Research Topics

Herpesvirus Infections and Treatments(91), T-cell and Retrovirus Studies(52), Immunotherapy and Immune Responses(48), Respiratory viral infections research(31), Viral gastroenteritis research and epidemiology(30)

Publications197 total

The biology and development of vaccines for bovine alphaherpesvirus 1
The Veterinary Journal·2024· 13 cited
Comprehensive Analysis of the Tegument Proteins Involved in Capsid Transport and Virion Morphogenesis of Alpha, Beta and Gamma Herpesviruses
Viruses·2023· 6 citedOpen Access
Bovine Herpesvirus-1 Glycoprotein M Mediates the Translocation to the Golgi Apparatus and Packaging of VP8
Viruses·2022· 6 citedOpen Access
VP8, the Major Tegument Protein of Bovine Herpesvirus-1, Is Partially Packaged during Early Tegument Formation in a VP22-Dependent Manner
Viruses·2021· 4 citedOpen Access
Chitosan nanoparticles fabricated through host-guest interaction for enhancing the immunostimulatory effect of CpG oligodeoxynucleotide
Carbohydrate Polymers·2021· 8 cited
Comprehensive Lipidomic and Metabolomic Analysis for Studying Metabolic Changes in Lung Tissue Induced by a Vaccine against Respiratory Syncytial Virus
ACS Infectious Diseases·2020· 22 cited
Low molecular weight chitosan nanoparticles for CpG oligodeoxynucleotides delivery: Impact of molecular weight, degree of deacetylation, and mannosylation on intracellular uptake and cytokine induction
International Journal of Biological Macromolecules·2020· 30 cited
Innate immunemodulator containing adjuvant formulated HA based vaccine protects mice from lethal infection of highly pathogenic avian influenza H5N1 virus
Vaccine·2020· 12 cited
Adjuvants: State of the Art and New Developments
Caister Academic Press eBooks·2020
Innate immune protection from pneumonia virus of mice induced by a novel immunomodulator is prolonged by dual treatment and mediated by macrophages
Antiviral Research·2019· 7 cited
Selection of adjuvants for vaccines targeting specific pathogens
Expert Review of Vaccines·2019· 114 citedOpen Access
Metabolomic and Immunological Profiling of Respiratory Syncytial Virus Infection after Intranasal Immunization with a Subunit Vaccine Candidate
Journal of Proteome Research·2019· 16 cited
US3 Kinase-Mediated Phosphorylation of Tegument Protein VP8 Plays a Critical Role in the Cellular Localization of VP8 and Its Effect on the Lipid Metabolism of Bovine Herpesvirus 1-Infected Cells
Journal of Virology·2019· 8 citedOpen Access
Maternal vaccination with a novel chimeric glycoprotein formulated with a polymer-based adjuvant provides protection from human parainfluenza virus type 3 in newborn lambs
Antiviral Research·2018· 11 cited
The bovine herpesvirus-1 major tegument protein, VP8, interacts with host HSP60 concomitant with deregulation of mitochondrial function
Virus Research·2018· 11 cited
A chimeric glycoprotein formulated with a combination adjuvant induces protective immunity against both human respiratory syncytial virus and parainfluenza virus type 3
Antiviral Research·2018· 16 cited
The Major Tegument Protein of Bovine Herpesvirus 1, VP8, Interacts with DNA Damage Response Proteins and Induces Apoptosis
Journal of Virology·2018· 21 citedOpen Access
The respiratory syncytial virus fusion protein formulated with a polymer-based adjuvant induces multiple signaling pathways in macrophages
Vaccine·2018· 5 cited
Vaccination with a human parainfluenza virus type 3 chimeric FHN glycoprotein formulated with a combination adjuvant induces protective immunity
Vaccine·2017· 23 cited
Defining a standard and weighted mathematical index for maturation of dendritic cells
Immunology·2017· 1 citedOpen Access
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Frequent Co-authors

Lorne A. Babiuk(40), Philip Griebel(9), Rolf Hecker(8), Reno Pontarollo(6), Volker Gerdts(6), J V van den Hurk(5), George Mutwiri(5), L. Latimer(5), Xenia P. Ioannou(4), Andrew Potter(4), John W. Mapletoft(4), Jennifer Kovacs-Nolan(4), Timothy J. Zamb(3), Shawn Babiuk(3), B Karvonen(3), Ravendra Garg(3), Ralph P. Braun(3), Robert Rankin(2), G. Hughes(2), Glen Gifford(2)