Jimena Pérez‐Vargas

University of British Columbia — Canada

Medicine · Health Sciences

16h-index881citations33works2.92yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(8), Hepatitis B Virus Studies(7), COVID-19 Clinical Research Studies(6), Hepatitis C virus research(6), Viral gastroenteritis research and epidemiology(4)

Publications33 total

TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infection
Emerging Microbes & Infections·2026Open Access
TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infection
Figshare·2026Open Access
TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infection
Figshare·2026Open Access
Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection
Autophagy Reports·2025Open Access
Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance
The Journal of Infectious Diseases·2025· 1 citedOpen Access
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants
Journal of Medicinal Chemistry·2025· 6 cited
Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals
Antiviral Research·2024· 13 citedOpen Access
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants
Emerging Microbes & Infections·2023· 17 citedOpen Access
Synthetic Analogs of the Sponge Sesterterpenoid Alotaketal C are Potent Inhibitors of SARS-CoV-2 Omicron BA.1 and BA.5 Infections of Human Lung Cells
Organic Letters·2023· 5 cited
P-91 Landscape of BRAF-V600E mutant colorectal cancer management in Latin America
Annals of Oncology·2023Open Access
Corrigendum to “Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics” “Antiviral Research 209 (2023)/105484”
Antiviral Research·2023Open Access
Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Emerging Microbes & Infections·2023· 18 citedOpen Access
Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Figshare·2023Open Access
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics
Antiviral Research·2022· 16 citedOpen Access
A fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process
eLife·2021· 25 citedOpen Access
HDV-Like Viruses
Viruses·2021· 33 citedOpen Access
Author response: A fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process
2021Open Access
Preliminary Evidence for Hepatitis Delta Virus Exposure in Patients Who Are Apparently Not Infected With Hepatitis B Virus
Hepatology·2020· 31 citedOpen Access
Le virus de l’hépatite Delta
médecine/sciences·2020Open Access
Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo
Nature Communications·2019· 130 citedOpen Access
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Frequent Co-authors

Connor A.H. Thompson(11), Siobhan Ennis(11), Masahiro Niikura(11), François Jean(10), Pierre‐Luc Boudreault(8), François–Loïc Cosset(7), F.A. Rey(5), Ivan Villanueva(5), Richard Leduc(5), Fouzia Amirache(4), Natália Freitas(4), Floriane Fusil(4), Pablo Guardado‐Calvo(4), Mel Krajden(4), Artem Cherkasov(4), Diana Bautista-Sánchez(4), Thomas Krey(3), Benjamin Podbilewicz(3), Bertrand Boson(3), Carlos F. Arias(3)