Michael D. W. Griffin

University of Melbourne — Australia

Medicine · Health Sciences

38h-index4.4kcitations166works3.32yr avg
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Research Topics

Alzheimer's disease research and treatments(33), Protein Structure and Dynamics(32), Enzyme Structure and Function(31), RNA and protein synthesis mechanisms(21), Biochemical and Molecular Research(18)

Publications166 total

Mechanism of NanR transcriptional activation of sialic acid metabolism in <i>Streptococcus pneumoniae</i>
2025Open Access
The Structure of the Apolipoprotein A-I Monomer Provides Insights Into Its Oligomerisation and Lipid-binding Mechanisms
Journal of Molecular Biology·2025· 1 citedOpen Access
Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target
PLoS Pathogens·2025· 1 citedOpen Access
Natural product-mediated reaction hijacking mechanism validates <i>Plasmodium</i> aspartyl-tRNA synthetase as an antimalarial drug target
2025· 1 citedOpen Access
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
PLoS Pathogens·2024· 2 citedOpen Access
The structure of the <scp>IL</scp>‐11 signalling complex provides insight into receptor variants associated with craniosynostosis
FEBS Journal·2024· 5 citedOpen Access
Heterochromatin protein 1 alpha (HP1α) undergoes a monomer to dimer transition that opens and compacts live cell genome architecture
Nucleic Acids Research·2024· 9 citedOpen Access
A potent and selective reaction hijacking inhibitor of <i>Plasmodium falciparum</i> tyrosine tRNA synthetase exhibits single dose oral efficacy <i>in vivo</i>
2024Open Access
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
eLife·2024· 7 citedOpen Access
Craniosynostosis‐associated variants in the <scp>IL‐11R</scp> complex: new insights and questions
FEBS Journal·2024· 3 citedOpen Access
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
Nature Communications·2024· 14 citedOpen Access
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
2024Open Access
Author Response: Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
2024Open Access
Unravelling the mechanism of neurotensin recognition by neurotensin receptor 1
Nature Communications·2023· 7 citedOpen Access
Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
Nature Communications·2023· 26 citedOpen Access
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
2023· 4 citedOpen Access
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
eLife·2023· 11 citedOpen Access
Structural and biophysical analysis of a <i>Haemophilus influenzae</i> tripartite ATP-independent periplasmic (TRAP) transporter
2023Open Access
Hijacking tRNA charging process: a novel approach to combat malaria
Acta Crystallographica Section A Foundations and Advances·2023
The structure and dynamics of lipid-free apolipoprotein A-I
Acta Crystallographica Section A Foundations and Advances·2023
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Frequent Co-authors

Renwick C. J. Dobson(12), Juliet A. Gerrard(11), Tracy L. Putoczki(9), Matthew A. Perugini(9), Geoffrey J. Howlett(8), Michael W. Parker(8), Riley D. Metcalfe(7), James M. Murphy(6), Paul R. Gooley(6), Katrina J. Binger(5), F. Grant Pearce(5), Craig J. Morton(5), Geoffrey B. Jameson(4), Matthias Ernst(4), Yee‐Foong Mok(4), Brian J. Smith(3), Isabelle S. Lucet(3), Weiwen Dai(3), Heath Ecroyd(3), Sarah C. Atkinson(3)