Phumla Sinxadi

South African Medical Research Council — South Africa

Medicine · Health Sciences

15h-index767citations72works5.42yr avg
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Research Topics

HIV/AIDS drug development and treatment(32), HIV Research and Treatment(27), HIV-related health complications and treatments(16), HIV/AIDS Research and Interventions(14), Pharmacogenetics and Drug Metabolism(8)

Publications72 total

The Effect of Rifampicin on the Plasma and Intracellular Pharmacokinetics of Tenofovir Alafenamide Fumarate in Participants with HIV-associated Tuberculosis
JAIDS Journal of Acquired Immune Deficiency Syndromes·2025
NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans
Frontiers in Genetics·2025· 1 citedOpen Access
Genetic polymorphisms and adverse reactions to antituberculosis therapy
Pharmacogenomics·2025Open Access
Pharmacokinetics, pharmacogenetics, and toxicity of co-administered efavirenz and isoniazid
Southern African Journal of HIV Medicine·2025Open Access
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
CPT Pharmacometrics & Systems Pharmacology·2024· 4 citedOpen Access
Cognitive performance, neuropsychiatric symptoms, and cerebrospinal fluid viral control following programmatic switch from efavirenz-based to dolutegravir-based antiretroviral therapy in South Africa (CONNECT): a prospective cohort study
The Lancet HIV·2024· 7 cited
Where does doravirine fit in current antiretroviral therapy?
The Lancet HIV·2024
The long wait for long-acting HIV prevention and treatment formulations
The Lancet HIV·2024· 20 cited
Genetic Variation in ABCB1, ADRB1, CYP3A4, CYP3A5, NEDD4L and NR3C2 Confers Differential Susceptibility to Resistant Hypertension among South Africans
Journal of Personalized Medicine·2024· 3 citedOpen Access
Management of drug-induced liver injury in people with HIV treated for tuberculosis: 2024 update
Southern African Journal of HIV Medicine·2024· 7 citedOpen Access
Obesity is South Africa’s new HIV epidemic
South African Medical Journal·2024· 3 citedOpen Access
Obesity is South Africa’s new HIV epidemic
South African Medical Journal·2024· 3 citedOpen Access
Pharmacokinetics of Single-Dose Versus Double-Dose Dolutegravir After Switching From a Failing Efavirenz-Based Regimen
JAIDS Journal of Acquired Immune Deficiency Syndromes·2024
Determinants of early change in serum creatinine after initiation of dolutegravir‐based antiretroviral therapy in South Africa
British Journal of Clinical Pharmacology·2024· 4 citedOpen Access
Final 192-Week Efficacy and Safety Results of the ADVANCE Trial, Comparing 3 First-line Antiretroviral Regimens
Open Forum Infectious Diseases·2024· 29 citedOpen Access
Lymphocyte Count Derived Polygenic Score and Interindividual Variability in CD4 T-cell Recovery in Response to Antiretroviral Therapy
2023Open Access
Major Genetic Drivers of Statin Treatment Response in African Populations and Pharmacogenetics of Dyslipidemia Through a One Health Lens
OMICS A Journal of Integrative Biology·2023· 1 citedOpen Access
Objectively measured medication adherence using assays for carvedilol and enalaprilat in patients with heart failure in Mozambique and Nigeria
International Journal of Cardiology Cardiovascular Risk and Prevention·2023· 4 citedOpen Access
Towards Evidence-Based Implementation of Pharmacogenomics in Southern Africa: Comorbidities and Polypharmacy Profiles across Diseases
Journal of Personalized Medicine·2023· 6 citedOpen Access
Towards Evidence-Based Implementation of Pharmacogenomics in Southern Africa: Comorbidities and Polypharmacy Profiles across Diseases
Preprints.org·2023· 2 citedOpen Access
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Frequent Co-authors

Gary Maartens(25), François Venter(16), David W. Haas(14), Lubbe Wiesner(14), Simiso Sokhela(13), Nomathemba Chandiwana(10), Paolo Denti(9), Joel A. Dave(7), Eric Decloedt(7), Godspower Akpomiemie(6), Yuki Bradford(6), Aida N. Kawuma(6), Roeland E. Wasmann(6), Helen McIlleron(5), Peter J. Smith(5), Naomi Levitt(5), Zinhle Cindi(5), Marylyn D. Ritchie(5), Andrew Hill(5), Collet Dandara(5)