Thomas E. Ryan

Covance (United States) — United States

Medicine · Health Sciences

16h-index1.1kcitations33works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(5), Advanced Biosensing Techniques and Applications(5), Glycosylation and Glycoproteins Research(4), Growth Hormone and Insulin-like Growth Factors(4), Metabolism, Diabetes, and Cancer(4)

Publications33 total

Carcinogenicity assessment of baricitinib in Tg.rasH2 mice and Sprague-Dawley (Crl:CD) rats
Regulatory Toxicology and Pharmacology·2017· 10 cited
Effects of the GLP-1 Receptor Agonist Dulaglutide on the Structure of the Exocrine Pancreas of Cynomolgus Monkeys
Toxicologic Pathology·2015· 7 cited
Chronic Toxicity and Carcinogenicity Studies of the Long-Acting GLP-1 Receptor Agonist Dulaglutide in Rodents
Endocrinology·2015· 31 citedOpen Access
Effects of Dulaglutide on Thyroid C Cells and Serum Calcitonin in Male Monkeys
Endocrinology·2015· 16 citedOpen Access
von Willebrand factor (VWF) propeptide binding to VWF D′D3 domain attenuates platelet activation and adhesion
Blood·2012· 49 citedOpen Access
Neoplastic and Non-neoplastic Changes in F-344 Rats Treated with Naveglitazar, a γ-Dominant PPAR α/γ Agonist
Toxicologic Pathology·2009· 24 cited
A global benchmark study using affinity-based biosensors
Analytical Biochemistry·2008· 97 citedOpen Access
Urothelial Carcinogenesis in the Urinary Bladder of Rats Treated with Naveglitazar, a γ-dominant PPAR α/γ Agonist: Lack of Evidence for Urolithiasis as an Inciting Event
Toxicologic Pathology·2008· 40 cited
Enhanced insulin‐like growth factor‐I (IGF‐I) cell association at reduced pH is dependent on IGF binding protein‐3 (IGFBP‐3) interaction
Journal of Cellular Physiology·2006· 4 cited
Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology
Analytical Biochemistry·2006· 116 cited
Real‐Time Analysis of Enzymatic Surface‐Initiated Polymerization Using Surface Plasmon Resonance (SPR)
Macromolecular Bioscience·2006· 15 cited
Increase in thyroid follicular cell tumors in nelfinavir-treated rats observed in a 2-year carcinogenicity study is consistent with a rat-specific mechanism of thyroid neoplasia
Human & Experimental Toxicology·2005· 18 cited
Mono and dithiol surfaces on surface plasmon resonance biosensors for detection of Staphylococcus aureus
Sensors and Actuators B Chemical·2005· 102 cited
A mixed self-assembled monolayer-based surface plasmon immunosensor for detection of E. coli O157:H7
Biosensors and Bioelectronics·2005· 274 cited
Ligand rebinding: self-consistent mean-field theory and numerical simulations applied to surface plasmon resonance studies
European Biophysics Journal·2005· 31 cited
Real-Time, label-free monitoring of tumor antigen and serum antibody interactions
Journal of Biochemical and Biophysical Methods·2004· 83 cited
Ligand Rebinding: Self-consistent Mean-field Theory and Numerical Simulations Applied to SPR Studies
arXiv (Cornell University)·2004· 2 citedOpen Access
<title>Refractive index-based detection of biomolecular interactions</title>
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE·2001· 2 cited
Medical Surveillance for Hematological Disorders Among Active and Retired Oil Refinery Workers
Journal of Occupational and Environmental Medicine·1998· 7 cited
Analysis of Water Content in Brake Fluid. Part I. Method Comparison: Karl Fisher Titration Versus Refractive Index
SAE technical papers on CD-ROM/SAE technical paper series·1997· 6 cited
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Frequent Co-authors

Adil E. Shamoo(5), Carl A. Batt(3), Gerald G. Long(3), Richard A. Byrd(3), Steven D. Sorden(3), Thomas P. Pienkowski(3), Jamie L. Blackbourne(3), Thomas J. Rosol(3), Jennifer A. Martin(3), John L. Vahle(3), Kimberly Forsten‐Williams(3), Anand Subramanian(2), Joseph Irudayaraj(2), Giuseppe A. Papalia(2), Phinikoula S. Katsamba(2), Anthony M. Giannetti(2), Jonathan Brooks(2), Yun Hee Cho(2), Christine Campagnolo(2), Robert Atkinson(2)