Jeffrey R. McArthur

Illawarra Health and Medical Research Institute — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index1.0kcitations54works8.32yr avg
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Research Topics

Ion channel regulation and function(38), Nicotinic Acetylcholine Receptors Study(33), Neuroscience and Neuropharmacology Research(14), Receptor Mechanisms and Signaling(13), Cardiac electrophysiology and arrhythmias(7)

Publications54 total

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties
Advanced Science·2025Open Access
Distinct molecular and functional properties of human induced-proprioceptor and low-threshold mechanoreceptor neurons
2024· 3 citedOpen Access
Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias
Nature Cardiovascular Research·2024· 29 citedOpen Access
Conservation of Ligand Binding Between Voltage-Gated Sodium and T-Type Calcium Channels
2024· 1 cited
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3
PLoS Biology·2023· 11 citedOpen Access
Automated Patch Clamp Screening of Amiloride and 5- <i>N</i> , <i>N</i> -Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor
Molecular Pharmaceutics·2023· 5 cited
Evidence of Cytolysin A nanopore incorporation in mammalian cells assessed by a graphical user interface
Nanoscale·2023· 2 citedOpen Access
Cellular Heterogeneity of Pluripotent Stem Cell Derived Cardiomyocyte Grafts is Mechanistically Linked to Treatable Arrhythmias
2022· 1 citedOpen Access
Analgesic α-Conotoxin Binding Site on the Human GABAB Receptor
Molecular Pharmacology·2022· 7 citedOpen Access
µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site
eLife·2022· 5 citedOpen Access
Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine
Frontiers in Molecular Neuroscience·2022· 17 citedOpen Access
Identification of a sensory neuron Cav2.3 inhibitor within a new superfamily of macro-conotoxins
2022· 1 citedOpen Access
Author response: µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site
2022Open Access
Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor
2022· 1 citedOpen Access
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider
Proceedings of the National Academy of Sciences·2022· 19 citedOpen Access
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation
British Journal of Pharmacology·2021· 18 citedOpen Access
μ-Theraphotoxin-Pn3a inhibition of Ca <sub>V</sub> 3.3 channels reveals a novel isoform-selective drug binding site
2021Open Access
Analgesic α‐conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABA <sub>B</sub> receptors and reduce neuroexcitability
British Journal of Pharmacology·2021· 16 citedOpen Access
In Vivo Survival and Differentiation of Friedreich Ataxia iPSC-Derived Sensory Neurons Transplanted in the Adult Dorsal Root Ganglia
Stem Cells Translational Medicine·2021· 8 citedOpen Access
Small-molecule mimicry hunting strategy in the imperial cone snail, <i>Conus imperialis</i>
Science Advances·2021· 27 citedOpen Access
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Frequent Co-authors

David J. Adams(30), Rocio K. Finol‐Urdaneta(29), Robert J. French(11), Baldomero M. Olivera(5), Andrew Hung(5), D. McMaster(4), Mirella Dottori(4), Anuja R. Bony(4), Ahmed Al-Sabi(3), Vitaly Ostroumov(3), Amy E. Hulme(3), Simon Maksour(3), Irina Vetter(3), Richard J. Lewis(3), Maren Watkins(3), Paula Flórez Salcedo(3), Helena Safavi‐Hemami(3), Stewart Heitmann(3), Jierong Wen(3), Min-Min Zhang(2)