Oleg V. Tsodikov

University of Kentucky — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

37h-index4.3kcitations155works1.92yr avg
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Research Topics

Biochemical and Molecular Research(33), DNA and Nucleic Acid Chemistry(31), Tuberculosis Research and Epidemiology(24), Enzyme Structure and Function(22), Bacterial Genetics and Biotechnology(18)

Publications155 total

Crystal structures and low-affinity complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
Bioscience Reports·2025Open Access
Abstract 4360: Development of a novel mithramycin analogue with improved pharmacokinetics and therapeutic window for targeted inhibition of EWS-FLI1 in Ewing sarcoma
Cancer Research·2025· 1 cited
The Position of Indole Methylation Controls the Structure, DNA Binding, and Cellular Functions of Mithramycin SA‐Trp Analogues
ChemBioChem·2025
Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites
Nucleic Acids Research·2025Open Access
Development of Zafirlukast Analogues for Improved Antithrombotic Activity Through Thiol Isomerase Inhibition
Arteriosclerosis Thrombosis and Vascular Biology·2025· 3 cited
Association of COVID-19 risk factors with systemic fungal infections in hospitalized patients
2024· 1 citedOpen Access
Transient interactions modulate the affinity of NF-κB transcription factors for DNA
Proceedings of the National Academy of Sciences·2024· 8 citedOpen Access
Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases
Natural Product Reports·2023· 27 cited
Finding of Widespread Viral and Bacterial Revolution dsDNA Translocation Motors Distinct from Rotation Motors by Channel Chirality and Size
2023
Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic
The FASEB Journal·2023· 11 citedOpen Access
Aromatic hydrazides: A potential solution for Acinetobacter baumannii infections
European Journal of Medicinal Chemistry·2023· 6 citedOpen Access
Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs
Biochemistry·2023· 7 citedOpen Access
Discovery and development of novel substituted monohydrazides as potent antifungal agents
RSC Medicinal Chemistry·2023Open Access
Identification and analysis of small molecule inhibitors of FosB from <i>Staphylococcus aureus</i>
RSC Medicinal Chemistry·2023· 3 citedOpen Access
Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis
Methods in enzymology on CD-ROM/Methods in enzymology·2023· 4 citedOpen Access
Inhibition of Fosfomycin Resistance Protein FosB from Gram-Positive Pathogens by Phosphonoformate
Biochemistry·2022· 6 citedOpen Access
A Colorimetric Assay to Identify and Characterize Bacterial Primase Inhibitors
Methods in molecular biology·2022
Mithplatins: Mithramycin SA‐Pt(II) Complex Conjugates for the Treatment of Platinum‐Resistant Ovarian Cancers
ChemMedChem·2022· 2 citedOpen Access
Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity
European Journal of Medicinal Chemistry·2022· 15 citedOpen Access
Discovery and Optimization of 6-(1-Substituted pyrrole-2-yl)-<i>s</i>-triazine Containing Compounds as Antibacterial Agents
ACS Infectious Diseases·2022· 10 cited
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Frequent Co-authors

Sylvie Garneau‐Tsodikova(19), Tapan Biswas(11), Keith Green(11), M. Thomas Record(10), Melisa J. Willby(8), James E. Posey(8), Ruth M. Saecker(6), Tom Ellenberger(5), Allan H. Pang(4), Atefeh Garzan(4), Chathurada S. Gajadeera(4), Caixia Hou(4), Orlando D. Schärer(3), Diane E. Frank(3), W. Michael(3), Sonya E. Melcher(3), Mark M. Levandoski(3), Huy Ngo(3), Irina A. Shkel(3), Irina Artsimovitch(3)