Isabelle Cleynen

Center for Human Genetics — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

48h-index13.3kcitations249works1.42yr avg
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Research Topics

Inflammatory Bowel Disease(141), Microscopic Colitis(57), Helicobacter pylori-related gastroenterology studies(55), Immunodeficiency and Autoimmune Disorders(30), Eosinophilic Esophagitis(20)

Publications248 total

Deciphering HTLV-1-associated Lung Pathology through Integrated in vitro and Multi-cohort Multi-omics Analysis: Inflammation, Monocyte Recruitment and Differentiation Triggered by HTLV-1-exposed Alveolar Epithelial Cells
2025Open Access
STREAM-PRS: a multi-tool pipeline for streamlining polygenic risk score computation
Genome Medicine·2025· 1 citedOpen Access
Genetic and clinical characteristics of familial pulmonary fibrosis patients and relatives
2025
Optimizing Polygenic Scores for Complex Morphological Traits: A Case Study in Nasal Shape Prediction
2025Open Access
Benchmarking long-read RNA-sequencing technologies with <i>LongBench:</i> a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches
2025· 4 citedOpen Access
Harmonizing genotype array data to understand genetic risk for brain amyloid burden in the AMYPAD PNHS Consortium
Alzheimer s & Dementia·2025· 1 citedOpen Access
Unravelling the genetic architecture of inflammatory bowel disease multiplex families with rare and common variant polygenic risk scores
Journal of Crohn s and Colitis·2025
IBD-linked Genetic Variance in Intestinal Transplantation
Annals of Surgery·2025· 1 citedOpen Access
Results of the Ninth Scientific Workshop of the European Crohn’s and Colitis Organisation (ECCO): Artificial intelligence in IBD surgery: opportunities and limitations
Journal of Crohn s and Colitis·2025· 1 citedOpen Access
Results of the 9th Scientific Workshop of the European Crohn’s and Colitis Organisation (ECCO): Artificial Intelligence in Endoscopy, Radiology and Histology in IBD Diagnostics
Journal of Crohn s and Colitis·2025· 5 citedOpen Access
Results of the 9th Scientific Workshop of the European Crohn’s and Colitis Organisation (ECCO): Artificial Intelligence in medical management and precision medicine
Journal of Crohn s and Colitis·2025· 2 citedOpen Access
Genotype imputation from low-coverage data for medical and population genetic analyses
Genome Research·2025Open Access
Results of the 9th Scientific Workshop of the European Crohn’s and Colitis Organisation (ECCO): Artificial Intelligence in IBD: Regulatory and Methodological Considerations
Journal of Crohn s and Colitis·2025Open Access
134: IBD-ASSOCIATED GENETIC VARIANCE IN DONORS AND RECIPIENTS ON INTESTINAL TRANSPLANT OUTCOME: INSIGHTS FROM A EUROPEAN MULTICENTER STUDY
Gastroenterology·2025
Multi-cohort cross-omics analysis reveals disease mechanisms and therapeutic targets in HTLV-1-associated myelopathy, a neglected retroviral neuroinflammatory disorder
2025· 2 citedOpen Access
Genomic prediction with kinship-based multiple kernel learning produces hypothesis on the underlying inheritance mechanisms of phenotypic traits
Genome biology·2025Open Access
P1292 Identifying genetic markers of fibrostenosis in patients with Crohn’s disease
Journal of Crohn s and Colitis·2025
P1290 Gene set polygenic risk scores identifies genetic subgroups in inflammatory bowel disease patients
Journal of Crohn s and Colitis·2025Open Access
Multi-Cohort Cross-Omics Analysis Reveals Disease Mechanisms and Therapeutic Targets in a Neglected Retroviral Neuroinflammatory Disorder
SSRN Electronic Journal·2025Open Access
Genetic modulators of diversity in biological expression of sickle cell anemia in patients from democratic republic of Congo
Mediterranean Journal of Hematology and Infectious Diseases·2024· 2 citedOpen Access
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Frequent Co-authors

Séverine Vermeire(36), Paul Rutgeerts(17), Gert Van Assche(16), Marc Ferrante(15), André Franke(8), Kristel Van Steen(8), Rinse K. Weersma(7), Stefan Schreiber(7), Ingrid Arijs(7), Gert De Hertogh(7), Richard H. Duerr(6), Philippe Goyette(6), Cisca Wijmenga(6), Bram Verstockt(6), Ann Gils(6), Thomas Billiet(6), Dermot McGovern(5), Emilie Théâtre(5), Mauro D’Amato(5), Michel Georges(5)