Lawrence M. Schopfer

Nebraska Medical Center — United States

Medicine · Health Sciences

45h-index6.4kcitations201works1.12yr avg
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Research Topics

Cholinesterase and Neurodegenerative Diseases(87), Pesticide Exposure and Toxicity(81), Computational Drug Discovery Methods(43), Pesticide and Herbicide Environmental Studies(27), Environmental Toxicology and Ecotoxicology(21)

Publications198 total

Validation and clinical evaluation of a comprehensive circulating tumor DNA assay for genomic profiling in solid tumors
BMC Cancer·2025Open Access
Kinetic analysis suggests that malathion at low environmental exposures is not toxic to humans
PLoS ONE·2025· 2 citedOpen Access
Validation and clinical evaluation of a comprehensive circulating tumor DNA assay for genomic profiling in solid tumors
2025Open Access
<i>Francisella tularensis</i> universal stress protein contributes to persistence during growth arrest and paraquat-induced superoxide stress
Journal of Bacteriology·2025Open Access
Old Yellow Enzyme
2024· 1 cited
Pharmacokinetics and fate of free and encapsulated IRD800CW-labelled human BChE intravenously administered in mice
International Journal of Biological Macromolecules·2024· 4 cited
Polyaminated, acetylated and stop codon readthrough of recombinant Francisella tularensis universal stress protein in Escherichia coli
PLoS ONE·2024· 2 citedOpen Access
Mass Spectrometry of Putrescine, Spermidine, and Spermine Covalently Attached to Francisella tularensis Universal Stress Protein and Bovine Albumin
Biochemistry Research International·2024Open Access
Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggregates
Chemico-Biological Interactions·2023· 22 citedOpen Access
Human butyrylcholinesterase in Cohn fraction IV-4 purified in a single chromatography step on Hupresin
PLoS ONE·2023· 16 citedOpen Access
Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking
Chemical Research in Toxicology·2023· 5 citedOpen Access
Contents: J. Plant Nutr. Soil Sci. 6/2022
Journal of Plant Nutrition and Soil Science·2022Open Access
Organophosphorus Pesticides Promote Protein Cross-Linking
Chemical Research in Toxicology·2022· 14 citedOpen Access
Dichlorvos-induced formation of isopeptide crosslinks between proteins in SH-SY5Y cells
Analytical Biochemistry·2022· 2 citedOpen Access
Chlorpyrifos oxon crosslinking of amyloid beta 42 peptides is a new route for generation of self-aggregating amyloidogenic oligomers that promote Alzheimer's disease
Chemico-Biological Interactions·2022· 9 citedOpen Access
Naturally Occurring Epsilon Gamma Glutamyl Lysine Isopeptide Crosslinks in Human Neuroblastoma SH-SY5Y Cells
ACS Omega·2022· 11 citedOpen Access
Butyrylcholinesterase in SH-SY5Y human neuroblastoma cells
NeuroToxicology·2022· 19 citedOpen Access
Rabbit Antidiethoxyphosphotyrosine Antibody, Made by Single B Cell Cloning, Detects Chlorpyrifos Oxon-Modified Proteins in Cultured Cells and Immunopurifies Modified Peptides for Mass Spectrometry
Journal of Proteome Research·2021· 10 citedOpen Access
Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides
PLoS ONE·2021· 9 citedOpen Access
Polyproline-Rich Peptides Organize Four Cholinesterase Subunits into a Tetramer; BChE and AChE Scavenge Polyproline Peptides Released during Metabolic Turnover
2020· 1 citedOpen Access
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Frequent Co-authors

Oksana Lockridge(38), Patrick Masson(22), Florian Nachon(12), Vincent Massey(10), Hasmik Grigoryan(6), Bin Li(4), Weihua Xie(4), Steven H. Hinrichs(4), Ellen G. Duysen(4), Marie-Thérèse Froment(4), E. Carletti(4), Weihua Xue(4), Charles M. Thompson(4), Stephen Brimijoin(3), He Li(3), Bin Li(3), Clement E. Furlong(3), Clarence A. Broomfield(2), Cynthia F. Bartels(2), Yvain Nicolet(2)