Gay M. Crooks

University of California, Los Angeles — United States

Medicine · Health Sciences

50h-index9.3kcitations215works7.02yr avg
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Research Topics

CAR-T cell therapy research(45), Hematopoietic Stem Cell Transplantation(42), Virus-based gene therapy research(33), Immune Cell Function and Interaction(28), CRISPR and Genetic Engineering(26)

Publications214 total

IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy
Immunity·2025Open Access
IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy
2025· 1 citedOpen Access
Stage-specific CAR-mediated signaling generates naïve-like, TCR-null CAR T cells from induced pluripotent stem cells
2024· 1 citedOpen Access
Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease
Molecular Therapy — Methods & Clinical Development·2024· 7 citedOpen Access
MYCT1 controls environmental sensing in human haematopoietic stem cells
Nature·2024· 13 citedOpen Access
Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency
Science Translational Medicine·2024· 20 citedOpen Access
Generation of antigen-specific mature T cells from RAG1−/−RAG2−/−B2M−/− stem cells by engineering their microenvironment
Nature Biomedical Engineering·2023· 10 citedOpen Access
MYCT1 Controls Environmental Sensing to Maintain Self-Renewal in Human Hematopoietic Stem Cells
Blood·2023Open Access
Cover 2: Editorial Board
Experimental Hematology·2023Open Access
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
Proceedings of the National Academy of Sciences·2023· 44 citedOpen Access
Artificial thymic organoids generated with peripheral blood CD34+ cells represent a quick and powerful tool to determine the nature of severe T cell lymphopenia
The Journal of Immunology·2023Open Access
Supplementary Data from IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System
2023Open Access
Supplementary Data from IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System
2023Open Access
Data from IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System
2023Open Access
Data from IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System
2023Open Access
Layered immune system development in mice and humans
Immunological Reviews·2023· 10 citedOpen Access
Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing
Cell·2023· 75 citedOpen Access
Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells
Cell Reports·2023· 19 citedOpen Access
Cover 2: Editorial Board
Experimental Hematology·2023Open Access
3016 – MYCT1 CONTROLS HUMAN HEMATOPOIETIC STEM CELL FUNCTION BY MODERATING ENDOCYTOSIS AND ENVIRONMENTAL SENSING
Experimental Hematology·2023
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Frequent Co-authors

Donald B. Kohn(18), Kenneth I. Weinberg(8), Lora W. Barsky(8), Yuhua Zhu(8), Shundi Ge(8), Christopher S. Seet(8), Robertson Parkman(7), Amélie Montel‐Hagen(6), Ami J. Shah(6), Chintan Parekh(6), Xiuli Wang(5), Qian‐Lin Hao(5), Jan A. Nolta(4), Mary Ann Price(4), Denis Evseenko(4), Judy Zhu(4), Michael S. Hershfield(3), R. Michael Blaese(3), E Smogorzewska(3), Neena Kapoor(3)