Frank Bretz

Novartis (Switzerland) — Switzerland

Mathematics · Physical Sciences

50h-index24.4kcitations312works2.22yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Statistical Methods in Clinical Trials(220), Optimal Experimental Design Methods(157), Health Systems, Economic Evaluations, Quality of Life(48), Advanced Statistical Methods and Models(46), Statistical Methods and Inference(45)

Publications311 total

Development of a consensus extension of the estimands framework for cluster randomised trials (CRT-estimands): results from an international Delphi study
Trials·2025Open Access
From Data to Knowledge. Advancing Life Sciences: Editorial for the CEN2023 Special Issue
Biometrical Journal·2025Open Access
Minimum Area Confidence Set Optimality for Simultaneous Confidence Bands for Percentiles With Applications to Drug Shelf‐Life Estimation
Statistics in Medicine·2025Open Access
Testing for Similarity of Dose Response in Multiregional Clinical Trials
Statistics in Medicine·2025Open Access
Exact two-sided confidence sets for a level set in simple linear regression
Annals of the Institute of Statistical Mathematics·2025
Statistical Challenges in the Conduct and Management of Ongoing Clinical Trials During the COVID-19 Pandemic
UNC Libraries·2025Open Access
Dose-response characterization: A key to success in drug development
Clinical Trials·2025· 1 cited
Development of a consensus extension of the estimands framework for cluster randomised trials (CRT-estimands): results from an international Delphi study
2025Open Access
Closed <scp>MCP</scp>‐Mod for Pairwise Comparisons of Several Doses With a Control
Statistics in Medicine·2025· 1 citedOpen Access
Randomization‐Based Inference for MCP‐Mod
Statistics in Medicine·2025· 1 citedOpen Access
Rejoinder to Commentaries on the “Monitoring OS in Pivotal Trials in Indolent Cancers” Article
Statistics in Biopharmaceutical Research·2025
Leveraging the Estimand Framework for Clinical Trial Disruptions
Springer series in pharmaceutical statistics·2025
Adaptive versus Fixed Designs in Confirmatory Clinical Trials: Centering the Choice on Ethics
SSRN Electronic Journal·2025Open Access
ICH Guidelines and Their Relationship to the Estimand Framework
Springer series in pharmaceutical statistics·2025
EMA Guidelines and Their Relationship to the Estimand Framework
Springer series in pharmaceutical statistics·2025
Leveraging the Estimand Framework Across Trial Designs
Springer series in pharmaceutical statistics·2025
Randomization-based Inference for MCP-Mod
arXiv (Cornell University)·2024Open Access
Rejoinder
Statistics in Biopharmaceutical Research·2024· 1 cited
Testing for similarity of multivariate mixed outcomes using generalized joint regression models with application to efficacy-toxicity responses
Biometrics·2024· 1 citedOpen Access
Monitoring Overall Survival in Pivotal Trials in Indolent Cancers
Statistics in Biopharmaceutical Research·2024· 9 citedOpen Access
page 1 of 16Next →

Frequent Co-authors

Torsten Hothorn(7), Alan Genz(7), Willi Maurer(7), Martin Posch(7), José Paulo Pinheiro(7), Björn Bornkamp(6), Heinz Schmidli(5), Peter H. Westfall(4), Werner Brannath(4), Holger Dette(4), Michael Branson(3), Franz König(3), Franz Koenig(3), Ekkehard Glimm(3), Michael Krams(3), Amy Racine(2), Vladimir Dragalin(2), Tetsuhisa Miwa(2), Xuefei Mi(2), Brenda Gaydos(2)