Jonathan J. Keats

Translational Genomics Research Institute — United States

Medicine · Health Sciences

54h-index13.0kcitations447works2.12yr avg
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Research Topics

Multiple Myeloma Research and Treatments(324), Protein Degradation and Inhibitors(119), Peptidase Inhibition and Analysis(51), Chronic Lymphocytic Leukemia Research(46), Cancer Genomics and Diagnostics(45)

Publications444 total

Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma
Blood Cancer Discovery·2025Open Access
ALTseqTM, a rapid (< 48 hours) whole genome sequencing clinical test for Acute Myeloid Leukemia (AML)
Blood·2025
Multiple myeloma genetic alterations have distinct repertoires and prognostic implications in African and european ancestries
Blood·2025Open Access
Transitioning from FISH to NGS for immunoglobulin translocation detection in multiple myeloma
Blood·2025Open Access
NSD2 expression remodels DNA methylation, creating a targetable epigenetic dependency in t(4;14) multiple myeloma
Blood·2025
Circulating tumor cells (CTCs) improve risk stratification according to the second revision of the international staging system (R2-ISS) and the ims-IMWG consensus genomic staging (CGS) in newly diagnosed multiple myeloma (NDMM): An analysis from the european CTC consortium.
Blood·2025Open Access
Elevated circulating tumor cells reflect high proliferation and genomic complexity in multiple myeloma
HemaSphere·2025· 3 citedOpen Access
Elevated Levels of Circulating Tumor Cells (CTCs) in Newly-Diagnosed Multiple Myeloma (NDMM) Patients Reflect a Highly Proliferative and Genomically Complex Profile
Clinical Lymphoma Myeloma & Leukemia·2025
Erratum: International Myeloma Society/International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma
Journal of Clinical Oncology·2025· 5 cited
International Myeloma Society/International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma
Journal of Clinical Oncology·2025· 78 citedOpen Access
Author Correction: Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes
Nature Genetics·2025Open Access
Longitudinal multi-omic profiling uncovers immune escape and predictors of response in multiple myeloma
2025Open Access
Association of HIPEC response in ovarian cancer with PI3K/RAS/Notch gene signatures: A whole transcriptomic analysis of U.S. and French HIPEC treated ovarian cancer patients.
Journal of Clinical Oncology·2025
Abstract 2047: Homologous recombination deficiency in lung cancer in the INSPIRE study
Cancer Research·2025
Large-scale human myeloma cell line small molecule compound screen dataset
Scientific Data·2025Open Access
Diploid genome assembly of human fibroblast cell lines enables clone specific variant calling, improved read mapping and accurate phasing
2025· 2 citedOpen Access
Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy
Scientific Reports·2024· 4 citedOpen Access
DNA Methylation Analysis of Commpass Reveals Distinct Epigenetic Programs of High-Risk Disease
Blood·2024Open Access
BCMA Extracellular Domain Functional Hotspots and Resistance to Variable Anti-BCMA T Cell Engagers in Multiple Myeloma
Blood·2024· 1 cited
Comprehensive Assessment of Immunoglobulin Translocation Detection in Multiple Myeloma By Whole Genome Sequencing
Blood·2024
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Frequent Co-authors

Daniel Auclair(13), P. Leif Bergsagel(13), A. Keith Stewart(13), Rafaël Fonseca(10), Sagar Lonial(9), Kenneth C. Anderson(8), Esteban Braggio(8), Linda M. Pilarski(8), Amrita Krishnan(7), Andrew R. Belch(7), Craig C. Hofmeister(6), S. Vincent Rajkumar(6), John D. Carpten(6), Marta Chesi(6), Niccolò Bolli(6), Gareth J. Morgan(6), Tony Reiman(6), Christopher A. Maxwell(6), Sundar Jagannath(5), Faith E. Davies(5)